Measurement of Lung Elastance and Transpulmonary Pressure Using Two Different Methods (Lungbarometry)
1 other identifier
observational
30
1 country
1
Brief Summary
Classically lung elastance and transpulmonary pressure are measured from the difference in tidal variations of airway pressure subtracted by tidal variations i esophagus pressure divided by the tidal volume. This requires the presence of a esophageal balloon catheter which is cumbersome and costly. In this study values obtained as described above are compared to values obtained with a new method in which a stepwise increase in positive endexpiratory pressure (PEEP) is performed with a size of the lung volume increase which corresponds to the tidal volume which the patient is ventilated with. The measurements are performed in sedated and mechanically ventilated patients in the intensive care unit.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for all trials
Started Oct 2016
Typical duration for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
October 1, 2016
CompletedFirst Submitted
Initial submission to the registry
October 26, 2016
CompletedFirst Posted
Study publicly available on registry
October 28, 2016
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 1, 2018
CompletedStudy Completion
Last participant's last visit for all outcomes
December 1, 2018
CompletedApril 11, 2018
April 1, 2018
2.2 years
October 26, 2016
April 10, 2018
Conditions
Outcome Measures
Primary Outcomes (1)
Measurement of lung elastance and transpulmonary pressure
Comparison of a new versus the classical method for measurement of transpulmonary pressure
Within one hour
Eligibility Criteria
Sedated and mechanically ventilated patients in the intensive care unit
You may qualify if:
- Mechanically ventilated patients in the intensive care unit
You may not qualify if:
- Patients with chronic obstrucive lung disease
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Stefan Lundinlead
Study Sites (1)
Sahlgrenska University Hospital
Gothenburg, S-413 45, Sweden
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Stefan Lundin, MD, PhD
Sahlgrenska University Hospital
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- CASE CROSSOVER
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR INVESTIGATOR
- PI Title
- Professor
Study Record Dates
First Submitted
October 26, 2016
First Posted
October 28, 2016
Study Start
October 1, 2016
Primary Completion
December 1, 2018
Study Completion
December 1, 2018
Last Updated
April 11, 2018
Record last verified: 2018-04