Chinese Arteriosclerosis Series Evaluation-She Minority Study

NCT02933957 | Unknown

• 1 other identifier: PUShougangH
• Study Type: observational
• Target: 300
• Locations: 1 country
• Sites: 1

Brief Summary

Traditionally, people have always been focusing on vascular injuries by angiography. Recent years, the investigators have further known that the pathological foundation of various cardiovascular complications not only lies in the vascular lumen, but also vessel wall. Therefore, now it is possible to detect and prevent vascular disease early. There are many influencing factors on functional and structural damages of vessels, including genetic and environmental factors. The investigators have done many researches on populations of the Han nationality, which has the largest population in China. Thus, the investigators further wonder whether the function and structure of vessel differ in the She Minority of a remote southern region in China. The investigators will enroll 150 subjects of two ethnic groups respectively in the local population， namely She Minority and Han nationality. All subjects enrolled into the study will complete a questionnaire survey of the general situation and conduct vascular related examinations, including evaluation of arterial stiffness, arterial elasticity indexes, subclinical carotid atherosclerosis and biomarkers. The investigators will analysis vascular differences between the two populations and provide a theoretical basis for the specific strategies of prevention and treatment.

Conditions

Vascular Disease

Keywords

Vascular Evaluation; influencing factor; She Minority population

Outcome Measures

Primary Outcomes (1)

• value of brachial ankle pulse wave velocity

  one and a half years

Secondary Outcomes (5)

• Percentage of flow mediated dilation

  one and a half years

• Value of arterial elasticity including stiffness coefficient β, pressure strain elastic coefficient, arterial compliance

  one and a half years

• Thickness of carotid intima-media by carotid ultrasound

  one and a half years

• Presence of Carotid Plaque

  one and a half years

• Number of peripheral arteriosclerosis occlusion measured by ankle brachial index

  one and a half years

Eligibility Criteria

• Age: 18 Years - 90 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Participants are natural population, from She Minority in Fujian province

You may qualify if:

• Voluntary participation

You may not qualify if:

• None

Sponsors & Collaborators

• Peking University Shougang Hospital: lead
• MinDong Hospital of Ningde City: collaborator

Study Sites (1)

Peking University Shougang Hospital

Beijing, Beijing Municipality, 100144, China

RECRUITING

MeSH Terms

Conditions

Vascular Diseases

Condition Hierarchy (Ancestors)

Cardiovascular Diseases

Central Study Contacts

Hong yu Wang, Doctor

CONTACT

+8610-57830226; hongyuwang@188.com

Study Design

• Study Type: observational
• Observational Model: ECOLOGIC OR COMMUNITY
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Director and Professor of Vascular Medicine

Study Record Dates

• First Submitted: October 8, 2016
• First Posted: October 14, 2016
• Study Start: January 1, 2015
• Primary Completion: October 1, 2017
• Last Updated: October 14, 2016

Record last verified: 2016-10

Locations

CN (1)