NCT05817487

Brief Summary

The goal of this study is to determine the effects of high-intensity interval training and crossover point exercise training on vascular health in young overweight women.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
20

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Feb 2019

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 18, 2019

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 5, 2019

Completed
4 months until next milestone

Study Completion

Last participant's last visit for all outcomes

October 25, 2019

Completed
3.4 years until next milestone

First Submitted

Initial submission to the registry

April 5, 2023

Completed
13 days until next milestone

First Posted

Study publicly available on registry

April 18, 2023

Completed
Last Updated

April 18, 2023

Status Verified

April 1, 2023

Enrollment Period

5 months

First QC Date

April 5, 2023

Last Update Submit

April 5, 2023

Conditions

Vascular Diseases

Outcome Measures

Primary Outcomes (2)

  • brachial-ankle pulse wave velocity (baPWV)

    The change of baPWV before and after intervention

    10 weeks

  • blood pressure

    The change of blood pressure before and after intervention

    10 weeks

Secondary Outcomes (2)

  • Interleukin 6 (IL-6)

    10 weeks

  • Homocysteine (HCY)

    10 weeks

Study Arms (2)

HIIT group

EXPERIMENTAL
Behavioral: high-intensity interval training (HIIT)

COP group

EXPERIMENTAL
Behavioral: crossover point(COP) exercise training

Interventions

high-intensity interval training (HIIT)BEHAVIORAL

Participants in both the COP and HIIT groups underwent 30 sessions of exercise performed over 10 weeks. The training sessions in the HIIT group involved five high-intensity intervals of 4 minutes each (running or walking on a treadmill) at 85% VO2max interspersed with 3 minutes of low-intensity walking.

HIIT group
crossover point(COP) exercise trainingBEHAVIORAL

Participants in both the COP and HIIT groups underwent 30 sessions of exercise performed over 10 weeks. The COP exercise training sessions involved 45 minutes of continuous exercise at the COP on a treadmill.

COP group

Eligibility Criteria

Age18 Years - 30 Years
Sexfemale
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Female, 18-30 years old
  • Body mass index (BMI) \< 28 kg/m2 and ≥ 24 kg/m2
  • No exercise habit, and no recent new exercise plan
  • No contraindications to exercise

You may not qualify if:

  • Participates had an orthopedic or other condition that limited participation in daily exercise
  • Participates had a history of myocardial infarction, stroke, diabetes mellitus, chronic respiratory disease or cancer
  • Participates had smoking or alcohol behavior

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Beijing Sport University

Beijing, China

Location

MeSH Terms

Conditions

Vascular Diseases

Interventions

High-Intensity Interval TrainingExercise

Condition Hierarchy (Ancestors)

Cardiovascular Diseases

Intervention Hierarchy (Ancestors)

Physical Conditioning, HumanMotor ActivityMovementMusculoskeletal Physiological PhenomenaMusculoskeletal and Neural Physiological Phenomena

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 5, 2023

First Posted

April 18, 2023

Study Start

February 18, 2019

Primary Completion

July 5, 2019

Study Completion

October 25, 2019

Last Updated

April 18, 2023

Record last verified: 2023-04

Locations

CN(1)