Memory and Attention in Healthy Children

NCT02858752 | Unknown

• 1 other identifier: 69HCL15_0711
• Study Type: interventional
• Target: 400
• Locations: 1 country
• Sites: 1

Brief Summary

This project studies memory and attention in healthy children aged from 5 to 17 years. The processes investigated are short term memory (auditory and visual) and attention. To characterize these processes involved in childhood, neuropsychological and neurophysiological assessments will be performed (using Electro-encephalography measures, behavioural responses and questionnaires).

Conditions

Healthy Volunteers

Keywords

Attention; Short-term memory; Aural Memory; Visual Memory; Child; EEG

Outcome Measures

Primary Outcomes (3)

• Neuropsychological tests: Proportion of accurate answers

  2 months

• Neuropsychological tests: reaction time of answers (seconds)

  2 months

• Neurophysiological tests: Event-related potentials in response to auditory and visual stimulations

  2 months

Secondary Outcomes (3)

• Proportion of accurate answers according to age range of children

  2 months

• reaction time of answers (seconds) according to age range of children

  2 months

• Event-related potentials in response to auditory and visual stimulations according to age range of children

  2 months

Study Arms (1)

Healthy Children

EXPERIMENTAL

Memory and Attention in healthy children will be assessed non-invasively through behavioral and electrophysiological measures while participants will perform passive or active computer task involving auditory and/or visual perception.

Other: Experience 1 : Auditory and Visual Discrimination; Other: Experience 2 : Passive and Active Auditory Perception; Other: Experience 3 : Visual Attention Training; Other: Experience 4 : Attention and Distractibility; Other: Experience 5 : Sustained Visual Attention

Interventions

Experience 1 : Auditory and Visual Discrimination OTHER

Neuropsychological tests consist in listening to sounds in various contexts and providing behavioral responses with response-buttons.

Healthy Children

Experience 2 : Passive and Active Auditory Perception OTHER

Neuropsychological tests consist in listening to sounds under 2 conditions, an active or a passive one, during which different auditory stimuli will be presented: frequent stimuli (standard) and rare stimuli (deviants). These two stimuli differ in some of their feature (height, duration, …). A third, very rare (novel) stimulus will also be used (the subject's first name). Responses will be provided using a response-button and feedback will be given at each response. EEG will be recorded all along to measure Neurophysiological signals.

Healthy Children

Experience 3 : Visual Attention Training OTHER

This experience aims at training visual attention through serious games. Children will play against an artificial intelligence and will focus their attention on one out of many possible targets (checkers, cards, boxes) presented on screen. Responses will be provided using a response-button, sometimes completed by an eye-tracking measure. Feedback will be given to the child after his response. EEG will be recorded all along to measure Neurophysiological signals.

Healthy Children

Experience 4 : Attention and Distractibility OTHER

Neuropsychological tests consist in listening to sounds preceded by a visual cue indicating (or not) in which ear the sounds will be played. The subject Child should detect the target sound (e.g. a dog barking). In some trials, a distracting distraction will be introduced between the visual cue and the target sound. Responses will be provided using a response-button. EEG will be recorded all along to measure Neurophysiological signals.

Healthy Children

Experience 5 : Sustained Visual Attention OTHER

Neuropsychological tests consist in watching visual stimuli presented in 3 blocks of 3 minutes each, with a break of one minute between each block. The child has to detect the presence of a red letter in a pattern made of four letters (the three other letters are black). Behavioral responses will be provided using a response-button. EEG will be recorded all along to measure Neurophysiological signals.

Healthy Children

Eligibility Criteria

• Age: 5 Years - 17 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17)

You may qualify if:

• Normal or corrected vision
• No neurological and psychiatric antecedent.
• No neuro-developmental disorder (dysphasia, dyslexia, dyspraxia, attention deficit disorder…)
• Motivation to participate to the study
• Signed parental informed consent authorizing their child to participate to the study

You may not qualify if:

• Children educated in a specialized institution.
• Subjects diagnosed with a neurological, psychiatric or neuro-developmental disorder
• Subjects with hearing loss
• Subjects with a visual impairment that cannot be corrected
• Subjects with an organic or chronic disease that can affect cognitive functions.
• Subjects who do not benefit from social security.

Sponsors & Collaborators

• Hospices Civils de Lyon: lead

Study Sites (1)

Hopital Femme Mère Enfant

Lyon, 69500, France

RECRUITING

Central Study Contacts

Julien JUNG, MD, PhD

CONTACT

(0)4 27 85 60 53; julien.jung@inserm.fr

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: BASIC SCIENCE
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 29, 2016
• First Posted: August 8, 2016
• Study Start: October 6, 2016
• Primary Completion: October 6, 2020
• Study Completion: October 6, 2020
• Last Updated: August 9, 2017

Record last verified: 2017-08

Data Sharing

• IPD Sharing: Will not share

Locations

FR (1)