NCT02855398|Completed
Decision-Making and the Relationship to Food Intake in Kids
DMK
Understanding Decision-Making and the Relationship to Food Intake in Children 7 to 11 Years Old
Loading search results
DMK
Understanding Decision-Making and the Relationship to Food Intake in Children 7 to 11 Years Old
Sponsor study identifier
observational
142
1 country
1
Study Start
April 2015
Actual (reported)Primary Completion
October 2016
Actual (reported)Study Completion
December 2017
Actual (reported)The purpose of this 18-month project is to investigate how decision-making influences food choice and consumption in children ages 7 to 11 years old. Although several studies suggest that the ability to make good decisions relates to eating behaviors, no studies have looked at how food reward influences the decision-making process to impact actual food intake. This proposal will answer these questions and bridge this gap in knowledge, which could lead to the development of more effective interventions for childhood obesity. To accomplish this, the investigators have assembled a diverse team with expertise in food intake, nutrition, and decision sciences. First, the investigators will establish if there are differences in decision-making between children varying in weight status. Second, the investigators will determine if performance on behavioral decision-making tasks relates to food consumption in the laboratory. Third, the investigators will examine response functional magnetic resonance imaging (fMRI) blood-oxygen-level-dependent (BOLD) response to various rewards (i.e. food and money) and determine if this is influenced by child weight status. Fourth, the investigators will examine differences in fMRI BOLD at rest in decision-making regions are correlated with food intake and weight status. Eighty-two children will participate in our study. The long-term goal of this project is to investigate if there are differences in brain regions corresponding to these behaviors in overweight children and if these differences relate to eating behaviors in this population. Children will undergo fMRI while playing a reward task as well as consume meals in our laboratory. Decision-making will also be assessed by having children complete various behavioral measurements of reward and inhibitory control.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
December 2017
Actual (reported)Click on a node to explore related trials.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
April 2015
Actual (reported)June 29, 2016
Actual (reported)August 4, 2016
Actual (reported)October 2016
Actual (reported)December 2017
Actual (reported)Functional magnetic resonance imaging (fMRI), blood-oxygen-level-dependent (BOLD) response to various reward types (food, money, no reward).
Regions of interest BOLD analysis of an fMRI card-guessing task for various reward types
Collected at fMRI scan at week 4
Functional magnetic resonance imaging (fMRI), blood-oxygen-level-dependent (BOLD) response at rest (resting-state fMRI)
Regions of interest BOLD analysis of resting-state fMRI to examine differences in brain regions of interest at rest
Collected at fMRI scan at week 4
Behavioral inhibitory control task
Measured by performance on a go/nogo task
Collected at either week 1-3 (randomized)
Behavioral reward inhibitory control task
Measured by performance on a go/nogo task with a reward incentive
Collected after the behavioral inhibitory control task (same visit), which is either week 1-3 (randomized)
Behavioral risk-taking and reward task
Measured by performance on the hungry donkey task
Collected at either week 1-3 (randomized)
Behavioral dietary self-control assessment
Measured by performance on a dietary self-control task
Collected at either week 1-3 (randomized)
Energy intake at baseline
Collected at either week 1-3 (randomized)
Energy intake at a buffet meal
Collected at either week 1-3 (randomized)
Energy intake after a meal preload
Collected at either week 1-3 (randomized) following the baseline meal
Functional magnetic resonance imaging (fMRI), blood-oxygen-level-dependent (BOLD) response to various reward types (food, money, no reward).
Collected at week 4
Functional magnetic resonance imaging (fMRI), blood-oxygen-level-dependent (BOLD) response at baseline
Collected at week 4
Liking of foods
Collected after each meal at multiple time points during weeks 1-4
Fullness feelings
Collected at multiple time points during weeks 1-4
Pubertal Development
Collected at week 1
Children aged 7-11 years old.
The Pennsylvania State University
University Park, Pennsylvania, 16802, United States
Adise S, White CN, Roberts NJ, Geier CF, Keller KL. Children's inhibitory control abilities in the presence of rewards are related to weight status and eating in the absence of hunger. Appetite. 2021 Dec 1;167:105610. doi: 10.1016/j.appet.2021.105610. Epub 2021 Jul 26.
Adise S, Geier CF, Roberts NJ, White CN, Keller KL. Is brain response to food rewards related to overeating? A test of the reward surfeit model of overeating in children. Appetite. 2018 Sep 1;128:167-179. doi: 10.1016/j.appet.2018.06.014. Epub 2018 Jun 8.
Shana Adise, B.S.
The Pennsylvania State University
142 participants (actual enrollment reported by the registry).
First Submitted
June 29, 2016
First Posted
August 4, 2016
Study Start
April 2015
Actual (reported)Using Herbs and Spices to Increase Children's Acceptance and Intake of Vegetables in School Lunches
Contact the study team to confirm eligibility.
Primary Completion
October 2016
Actual (reported)Study Completion
December 2017
Actual (reported)Last Updated
January 11, 2021
Record last verified: 2021-01
Download the complete ClinicalTrials.gov record imported by Syfrah, including fields not shown in this page. The registry may contain a newer revision.
Source: ClinicalTrials.gov.
JSON downloads include source attribution and retrieval details alongside the unchanged original record or the separately normalized values.
Source retrieved: