Aphasia Therapy: Factors of Efficacy
Constraint Induced Aphasia Therapy in Stroke Patients in Acute Stage.
1 other identifier
interventional
60
0 countries
N/A
Brief Summary
Constraint-induced aphasia therapy (CIAT) has proven effective in stroke patients. It has remained unclear, however, whether intensity of therapy or constraint is the relevant factor. This study will give an answer to this question to improve speech and language therapy.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable
Started Mar 2005
Longer than P75 for not_applicable
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
March 1, 2005
CompletedPrimary Completion
Last participant's last visit for primary outcome
January 1, 2013
CompletedStudy Completion
Last participant's last visit for all outcomes
March 1, 2013
CompletedFirst Submitted
Initial submission to the registry
June 9, 2016
CompletedFirst Posted
Study publicly available on registry
June 17, 2016
CompletedJune 17, 2016
June 1, 2016
7.8 years
June 9, 2016
June 14, 2016
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Change of aphasia by Aachener Aphasia Test (AAT)
pretreatment and within 24 h post intervention
Secondary Outcomes (1)
Change of Communication Activity Log (CAL)
pretreatment and within 24 h post intervention
Study Arms (3)
Control group
ACTIVE COMPARATORPatients received a standard, house-typical aphasia therapy in single and group therapy sessions
CIAT-group
EXPERIMENTALPatients received constraint-induced aphasia therapy.
communication treatment group (CTG)
ACTIVE COMPARATORPatients received aphasia group therapy without constraints
Interventions
Examine the efficacy of CIAT (30 h over 10 workdays) versus Control-group and communication treatment group.
Examine the efficacy of CTG (30h over 10 wokrdays) versus CIAT-group and control group
Eligibility Criteria
You may qualify if:
- first ever stroke
- suffering from aphasia
You may not qualify if:
- severe cognitive or attentional impairments
- severe depression
- left-handedness
- severe dysarthria
- apraxia of speech
- severe deafness
- additional neurological diseases affecting speech (e.g. Parkinson's disease)
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Related Publications (1)
Woldag H, Voigt N, Bley M, Hummelsheim H. Constraint-Induced Aphasia Therapy in the Acute Stage: What Is the Key Factor for Efficacy? A Randomized Controlled Study. Neurorehabil Neural Repair. 2017 Jan;31(1):72-80. doi: 10.1177/1545968316662707. Epub 2016 Aug 9.
PMID: 27506677DERIVED
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Hartwig Woldag, PhD
NRZ Leipzig
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- OUTCOMES ASSESSOR
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Head of departement NRZ Leipzig
Study Record Dates
First Submitted
June 9, 2016
First Posted
June 17, 2016
Study Start
March 1, 2005
Primary Completion
January 1, 2013
Study Completion
March 1, 2013
Last Updated
June 17, 2016
Record last verified: 2016-06
Data Sharing
- IPD Sharing
- Will not share