NCT06990997

Brief Summary

The goal of this clinical trial is to learn whether healthy volunteers are more successful at understanding people with aphasia if they have first viewed an aphasia identification (ID) card. The main questions this study aims to answer are:

  • Does viewing an aphasia ID card improve healthy volunteers' understanding of the language errors made by people with aphasia?
  • Does viewing an aphasia ID card improve healthy volunteers' understanding of people with aphasia who make long pauses in their speech? Researchers will compare aphasia ID cards to a control condition (no ID card) to see whether aphasia ID cards improve healthy volunteers' understanding. Healthy volunteers will visit the study site for a single session (about 2 hours long). During the session they will:
  • Complete brief tests of their vision, hearing and thinking
  • Listen to sentences produced by a speaker with aphasia while their eye movements are recorded
  • Complete a survey about the experience of listening to the speaker with aphasia

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
160

participants targeted

Target at P75+ for not_applicable

Timeline
1mo left

Started Sep 2025

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress85%
Sep 2025Aug 2026

First Submitted

Initial submission to the registry

May 1, 2025

Completed
24 days until next milestone

First Posted

Study publicly available on registry

May 25, 2025

Completed
4 months until next milestone

Study Start

First participant enrolled

September 22, 2025

Completed
10 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2026

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2026

Last Updated

April 29, 2026

Status Verified

April 1, 2026

Enrollment Period

10 months

First QC Date

May 1, 2025

Last Update Submit

April 28, 2026

Conditions

Keywords

AphasiaCommunication partnerService workerLanguage processingLanguage comprehensionaphasia identification cardeye-tracking

Outcome Measures

Primary Outcomes (2)

  • Comprehension accuracy for sentences with long pauses in the Service Request Comprehension Task

    Percent correct mouse-click responses on the Service Request Comprehension Task for sentences with long pauses. The Service Request Comprehension Task measures participants' comprehension and processing of language produced by a speaker with aphasia.

    5 minutes post-intervention

  • Comprehension accuracy for sentences with paraphasias in the Service Request Comprehension Task

    Percent correct mouse-click responses on the Service Request Comprehension Task for sentences with paraphasias (word-retrieval errors). The Service Request Comprehension Task measures participants' comprehension and processing of language produced by a speaker with aphasia.

    5 minutes post-intervention

Secondary Outcomes (6)

  • Visual attention during long pauses in the Service Request Comprehension Task

    5 minutes post-intervention

  • Linguistic integration of words immediately following long pauses in the Service Request Comprehension Task

    5 minutes post-intervention

  • Implicit repair of paraphasias in the Service Request Comprehension Task

    5 minutes post-intervention

  • Rating of own patience on the Attitude Survey

    0 minutes (immediately) post-intervention, 45 minutes post-intervention

  • Rating of speaker with aphasia's intelligence on the Attitude Survey

    0 minutes (immediately) post-intervention, 45 minutes post-intervention

  • +1 more secondary outcomes

Study Arms (2)

Aphasia Identification Card

EXPERIMENTAL

Participants will view an aphasia ID card for a speaker with aphasia. The card will disclose the speaker's aphasia, define aphasia, and request time to communicate.

Behavioral: Aphasia identification (ID) card

No Card

NO INTERVENTION

Participants in this arm will not receive an intervention.

Interventions

Participants will view an aphasia ID card for a speaker with aphasia. The card will disclose the speaker's aphasia, define aphasia, and request time to communicate.

Aphasia Identification Card

Eligibility Criteria

Age18 Years - 59 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Adult age 18-59
  • Currently employed as a service worker
  • Understand spoken and written English well
  • High school diploma or equivalency
  • Normal vision or corrected vision with glasses or contact lenses

You may not qualify if:

  • Language disorder
  • Hearing impairment
  • Intellectual disability
  • History of acquired neurological disorder (e.g., stroke or moderate/severe brain injury)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

UMass Amherst Henry M. Thomas III Center at Springfield

Springfield, Massachusetts, 01115, United States

RECRUITING

MeSH Terms

Conditions

Aphasia

Condition Hierarchy (Ancestors)

Speech DisordersLanguage DisordersCommunication DisordersNeurobehavioral ManifestationsNeurologic ManifestationsNervous System DiseasesSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Jennifer Mack, PhD

    University of Massachusetts, Amherst

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Jennifer E Mack, PhD

CONTACT

Holly Laws, PhD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Professor

Study Record Dates

First Submitted

May 1, 2025

First Posted

May 25, 2025

Study Start

September 22, 2025

Primary Completion (Estimated)

August 1, 2026

Study Completion (Estimated)

August 1, 2026

Last Updated

April 29, 2026

Record last verified: 2026-04

Data Sharing

IPD Sharing
Will share

Data to be generated from this project include language processing data collected through eye-tracking, comprehension accuracy data (mouse-click responses), and participants' responses to a survey measuring their attitudes. De-identified raw survey data and comprehension accuracy data will be preserved and shared. Deidentified, preprocessed eye-tracking data will be preserved and shared.

Shared Documents
STUDY PROTOCOL
Time Frame
De-identified data will be available upon publication of related work or the end of the project period, whichever comes first, and will remain available indefinitely.
Access Criteria
IPD and supporting information will be freely available on Open Science Framework.

Locations