Identification of Morphological Characteristics to Predict Difficult Endotracheal Intubation Using a Flexible Fiberscope

NCT02769819 | Completed

• 1 other identifier: 16.051
• Study Type: interventional
• Target: 420
• Locations: 1 country
• Sites: 1

Brief Summary

This study is designed to identify patients' features predictive of difficult endotracheal intubation using a flexible fiberscope.

Conditions

Intubation; Difficult

Keywords

Flexible fiberscope

Outcome Measures

Primary Outcomes (1)

• Morphologic and morphometric predictors of difficult intubation with the flexible fiberscope.

  This study will correlate patients' morphometric and morphologic characteristics with the number of attempts and time needed for intubation using a flexible fiberscope.

  Patients will be followed from induction of anesthesia until the end of intubation, an average of 10 minutes

Secondary Outcomes (3)

• Time to successful intubation

  Patients will be followed from induction of anesthesia until the end of intubation, an average of 10 minutes

• Number of attempts to successful intubation

  Patients will be followed from induction of anesthesia until the end of intubation, an average of 10 minutes

• Score on the Intubation Difficulty Scale

  Patients will be followed from induction of anesthesia until the end of intubation, an average of 10 minutes

Study Arms (1)

Intubation with a flexible fiberscope

EXPERIMENTAL

Following induction of general anesthesia and administration of a neuromuscular blocking agent, intubation will be performed using a flexible fiberscope.

Device: Flexible fiberscope

Interventions

Flexible fiberscope DEVICE

* Characteristics of patients will be assessed before induction of general anesthesia * Glottic visualization will be evaluated by direct laryngoscopy. * The endotracheal tube will be loaded onto the scope after silicon spray lubrication * Intubation will be performed with the flexible fiberscope with the patient in supine position with head and neck in neutral position * With the tip of the fiberscope in satisfactory position, the endotracheal tube will be advanced into the trachea. The scope will then be removed. * Accurate positioning of the endotracheal tube will be confirmed by capnography and lung auscultation.

Intubation with a flexible fiberscope

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Age 18 and older
• Patients undergoing elective surgery under general anesthesia, requiring endotracheal intubation

You may not qualify if:

• Induction planned without neuromuscular blocking agents
• Need for a rapid sequence induction

Sponsors & Collaborators

• Centre hospitalier de l'Université de Montréal (CHUM): lead

Study Sites (1)

Centre Hospitalier de l'Université de Montréal (CHUM)

Montreal, Quebec, H2L 4M1, Canada

Location

Related Publications (1)

• Toure T, Williams SR, Kerouch M, Ruel M. Patient factors associated with difficult flexible bronchoscopic intubation under general anesthesia: a prospective observational study. Can J Anaesth. 2020 Jun;67(6):706-714. doi: 10.1007/s12630-020-01568-w. Epub 2020 Jan 17.

  PMID: 31953669 DERIVED

Study Officials

• Stephan R Williams, MD, PhD

  Centre hospitalier de l'Université de Montréal (CHUM)

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: OTHER
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: May 10, 2016
• First Posted: May 12, 2016
• Study Start: October 1, 2016
• Primary Completion: September 12, 2017
• Study Completion: September 12, 2017
• Last Updated: October 9, 2017

Record last verified: 2017-10

Locations

CA (1)