NCT02744885

Brief Summary

The purpose of the research is to determine if participants who take "Crave Crush" will report lower cravings and palatability ratings of candy as compared to subjects who receive the placebo. Participants are self-selected university students who pass our table and verbally agree to participate in a research study about taste preferences. Data will be recorded anonymously.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
67

participants targeted

Target at P50-P75 for not_applicable obesity

Timeline
Completed

Started Feb 2016

Shorter than P25 for not_applicable obesity

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 1, 2016

Completed
29 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2016

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2016

Completed
17 days until next milestone

First Submitted

Initial submission to the registry

April 18, 2016

Completed
2 days until next milestone

First Posted

Study publicly available on registry

April 20, 2016

Completed
Last Updated

July 19, 2018

Status Verified

July 1, 2018

Enrollment Period

29 days

First QC Date

April 18, 2016

Last Update Submit

July 17, 2018

Conditions

Obesity

Outcome Measures

Primary Outcomes (1)

  • Self-Reported Craving Reduction

    10 minutes

Secondary Outcomes (1)

  • Self-Reported Palatability Reduction

    10 minutes

Study Arms (2)

Crave Crush

EXPERIMENTAL

Crave Crush is a plant-based tablet that alters taste perception by affecting sweet taste receptors on the tongue.

Dietary Supplement: Crave Crush

Placebo

PLACEBO COMPARATOR

The placebo tablet is comparable in taste and is comprised primarily of sorbitol.

Dietary Supplement: Placebo Comparator: Placebo

Interventions

Crave CrushDIETARY_SUPPLEMENT

Crave Crush is a dietary supplement that affects sweet taste receptors on the tongue.

Crave Crush
Placebo Comparator: PlaceboDIETARY_SUPPLEMENT

The placebo tablet is comparable in taste and is comprised primarily of sorbitol.

Placebo

Eligibility Criteria

Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • University student, having eaten within the last hour, having slept within two hours of their normal amount

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (1)

  • Stice E, Yokum S, Gau JM. Gymnemic acids lozenge reduces short-term consumption of high-sugar food: A placebo controlled experiment. J Psychopharmacol. 2017 Nov;31(11):1496-1502. doi: 10.1177/0269881117728541. Epub 2017 Sep 25.

    PMID: 28944714DERIVED

MeSH Terms

Conditions

Obesity

Condition Hierarchy (Ancestors)

OverweightOvernutritionNutrition DisordersNutritional and Metabolic DiseasesBody WeightSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
BASIC SCIENCE
Intervention Model
PARALLEL
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 18, 2016

First Posted

April 20, 2016

Study Start

February 1, 2016

Primary Completion

March 1, 2016

Study Completion

April 1, 2016

Last Updated

July 19, 2018

Record last verified: 2018-07

Data Sharing

IPD Sharing
Will not share