NCT02660671

Brief Summary

This is an RCT aimed at testing different population-based approaches to increasing colorectal cancer screening through email outreach, including usual email communication, active choice, and active choice + financial incentive.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
2,250

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Jan 2016

Shorter than P25 for not_applicable

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2016

Completed
18 days until next milestone

First Submitted

Initial submission to the registry

January 19, 2016

Completed
2 days until next milestone

First Posted

Study publicly available on registry

January 21, 2016

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2016

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2016

Completed
Last Updated

May 5, 2017

Status Verified

May 1, 2017

Enrollment Period

7 months

First QC Date

January 19, 2016

Last Update Submit

May 3, 2017

Conditions

Cancer of the Colon

Outcome Measures

Primary Outcomes (1)

  • Colonoscopy participation

    The percentage of participants who follow through with screening colonoscopy.

    3 months

Secondary Outcomes (2)

  • Email engagement

    3 months

  • Scheduling of colonoscopy

    3 months

Study Arms (3)

Usual care

ACTIVE COMPARATOR

Email outreach

Behavioral: Email outreach

Active choice

EXPERIMENTAL

Email outreach + active choice

Behavioral: Email outreachBehavioral: Active choice

Financial incentive + Active choice

EXPERIMENTAL

Email outreach + active choice + financial incentive

Behavioral: Email outreachBehavioral: Active choiceBehavioral: Financial incentive

Interventions

Email outreachBEHAVIORAL

Subjects will receive an email describing the importance of colorectal cancer screening and that s/he has been selected to participate in this VIP concierge service.

Active choiceFinancial incentive + Active choiceUsual care
Active choiceBEHAVIORAL

S/he will receive the ability to pre-commit and choose from 3 different appointment slots by clicking directly on the email.

Active choiceFinancial incentive + Active choice
Financial incentiveBEHAVIORAL

The participant will receive the offering of $100 if s/he follows through with screening colonoscopy.

Financial incentive + Active choice

Eligibility Criteria

Age50 Years - 64 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Male and female employees of the University of Pennsylvania Health System who live within 30 miles of a health system endoscopy center.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (1)

  • Mehta SJ, Feingold J, Vandertuyn M, Niewood T, Cox C, Doubeni CA, Volpp KG, Asch DA. Active Choice and Financial Incentives to Increase Rates of Screening Colonoscopy-A Randomized Controlled Trial. Gastroenterology. 2017 Nov;153(5):1227-1229.e2. doi: 10.1053/j.gastro.2017.07.015. Epub 2017 Jul 20.

    PMID: 28734830DERIVED

MeSH Terms

Conditions

Colonic Neoplasms

Condition Hierarchy (Ancestors)

Colorectal NeoplasmsIntestinal NeoplasmsGastrointestinal NeoplasmsDigestive System NeoplasmsNeoplasms by SiteNeoplasmsDigestive System DiseasesGastrointestinal DiseasesColonic DiseasesIntestinal Diseases

Study Officials

  • Shivan Mehta, MD

    University of Pennsylvania

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
INVESTIGATOR
Purpose
HEALTH SERVICES RESEARCH
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 19, 2016

First Posted

January 21, 2016

Study Start

January 1, 2016

Primary Completion

August 1, 2016

Study Completion

September 1, 2016

Last Updated

May 5, 2017

Record last verified: 2017-05