NCT03021759

Brief Summary

In this study, the investigators will conduct a pragmatic, cluster-randomized, controlled trial to evaluate an active choice intervention with and without social comparison feedback to increase physician statin prescribing rates for eligible patients.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
4,774

participants targeted

Target at P75+ for not_applicable cardiovascular-diseases

Timeline
Completed

Started Feb 2017

Shorter than P25 for not_applicable cardiovascular-diseases

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

January 12, 2017

Completed
4 days until next milestone

First Posted

Study publicly available on registry

January 16, 2017

Completed
1 month until next milestone

Study Start

First participant enrolled

February 21, 2017

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 21, 2017

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 21, 2017

Completed
2.2 years until next milestone

Results Posted

Study results publicly available

June 20, 2019

Completed
Last Updated

June 20, 2019

Status Verified

March 1, 2019

Enrollment Period

2 months

First QC Date

January 12, 2017

Results QC Date

October 30, 2018

Last Update Submit

March 20, 2019

Conditions

Cardiovascular Diseases

Outcome Measures

Primary Outcomes (1)

  • Statin Prescribing Rate

    Percentage of patients eligible for a statin that have been prescribed a statin

    Two Months

Study Arms (3)

Control

NO INTERVENTION

No intervention

Active choice

EXPERIMENTAL

Physicians will be asked to review a list of their patients eligible for statin therapy who are not yet prescribed a statin and make an active choice whether or not to prescribe a statin.

Behavioral: Active choice

Active choice with social comparison feedback

EXPERIMENTAL

Physicians will be asked to review a list of their patients eligible for statin therapy who are not yet prescribed a statin and make an active choice whether or not to prescribe a statin. Physicians will receive social comparison feedback informing them of how their performance compares to their peers

Behavioral: Active choiceBehavioral: Social comparison feedback

Interventions

Active choiceBEHAVIORAL

Statin options are framed to physicians as an active choice to prescribe or not prescribe a statin

Active choiceActive choice with social comparison feedback
Social comparison feedbackBEHAVIORAL

Statin prescribing rates are communicated to physicians and along with how their performance compares to their peers

Active choice with social comparison feedback

Eligibility Criteria

Age40 Years - 75 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patient has a primary care physician at University of Pennsylvania Health System
  • Patient meets 2013 AHA/ACC guidelines for statin therapy but no record of a statin prescription in the electronic health record

You may not qualify if:

  • Patient has an allergy or adverse reaction to statins documented in the electronic health record
  • Patient has glomerular filtration rate less than 30 mL/min
  • Physicians (and their respective patients) will be excluded if they have less than 10 patients among their entire panel that are eligible for a statin

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Pennsylvania Health System

Philadelphia, Pennsylvania, 19104, United States

Location

Related Publications (1)

  • Patel MS, Kurtzman GW, Kannan S, Small DS, Morris A, Honeywell S Jr, Leri D, Rareshide CAL, Day SC, Mahoney KB, Volpp KG, Asch DA. Effect of an Automated Patient Dashboard Using Active Choice and Peer Comparison Performance Feedback to Physicians on Statin Prescribing: The PRESCRIBE Cluster Randomized Clinical Trial. JAMA Netw Open. 2018 Jul 6;1(3):e180818. doi: 10.1001/jamanetworkopen.2018.0818.

    PMID: 30646039DERIVED

MeSH Terms

Conditions

Cardiovascular Diseases

Limitations and Caveats

Physicians and patients were from a single health care system and we did not have data on prescription fill rates.

Results Point of Contact

Title
Rebecca Pepe
Organization
University of Pennsylvania
peper@pennmedicine.upenn.edu
215-360-0951

Study Officials

  • Mitesh Patel, MD, MBA, MS

    University of Pennsylvania

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
INVESTIGATOR
Purpose
HEALTH SERVICES RESEARCH
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 12, 2017

First Posted

January 16, 2017

Study Start

February 21, 2017

Primary Completion

April 21, 2017

Study Completion

April 21, 2017

Last Updated

June 20, 2019

Results First Posted

June 20, 2019

Record last verified: 2019-03

Locations

US(1)