Financial Incentives to Improve Acceptance of Antipsychotic Injections
1 other identifier
interventional
20
0 countries
N/A
Brief Summary
There is a lack of incentive approach for patients who suffer from schizophrenia yet lack the insight to accept treatment. Most existing approaches involve coercion and involuntary hospitalizations. This study will explore whether patients with poor insight and lacking in competence for treatment decisions will improve their acceptance and adherence of depot injection antipsychotic medication if a financial incentive is offered. Ethical considerations are also explored for this innovative pilot study
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable schizophrenia
Started Jul 2017
Longer than P75 for not_applicable schizophrenia
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
June 15, 2017
CompletedFirst Posted
Study publicly available on registry
June 20, 2017
CompletedStudy Start
First participant enrolled
July 1, 2017
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 31, 2019
CompletedStudy Completion
Last participant's last visit for all outcomes
December 31, 2021
CompletedJune 20, 2017
June 1, 2017
2.5 years
June 15, 2017
June 18, 2017
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Adherence to depot injection
The primary outcome is adherence to depot medication during the 18-month study period. Adherence will be measured, objectively, as the percentage of prescribed depot injections actually taken.
18 months
Secondary Outcomes (12)
The time 'delayed' in taking depot
18 months
Clinical status
18 months
Psychosocial status
18 months
Number of involuntary and voluntary hospital admissions
18 months
Number of attempted and completed suicides
18 months
- +7 more secondary outcomes
Study Arms (2)
with financial incentive
EXPERIMENTALPatients randomized to this arm will start with receiving the financial incentive. Cross-over after 9 months to treatment as usual.
treatment as usual
NO INTERVENTIONPatients randomized to this arm will start with receiving treatment as usual, cross-over after 9 months to incentive arm.
Interventions
Eligibility Criteria
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Related Publications (1)
Priebe S, Burton A, Ashby D, Ashcroft R, Burns T, David A, Eldridge S, Firn M, Knapp M, McCabe R. Financial incentives to improve adherence to anti-psychotic maintenance medication in non-adherent patients - a cluster randomised controlled trial (FIAT). BMC Psychiatry. 2009 Sep 28;9:61. doi: 10.1186/1471-244X-9-61.
PMID: 19785727RESULT
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- OTHER
- Intervention Model
- CROSSOVER
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Staff Psychiatrist
Study Record Dates
First Submitted
June 15, 2017
First Posted
June 20, 2017
Study Start
July 1, 2017
Primary Completion
December 31, 2019
Study Completion
December 31, 2021
Last Updated
June 20, 2017
Record last verified: 2017-06
Data Sharing
- IPD Sharing
- Will not share