NCT03068052

Brief Summary

This is an RCT among UPHS employees between ages 50-64 comparing no incentive and a loss-framed incentive for completing cancer health risk assessment. Those eligible will receive the phone number for direct colonoscopy scheduling, with the incentive arm receiving an additional unconditional incentive. The primary outcome is completion of screening colonoscopy. Secondary outcomes include scheduling of colonoscopy and completion of risk assessment.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
2,000

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started May 2017

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

February 24, 2017

Completed
5 days until next milestone

First Posted

Study publicly available on registry

March 1, 2017

Completed
2 months until next milestone

Study Start

First participant enrolled

May 8, 2017

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 8, 2017

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

November 8, 2017

Completed
Last Updated

February 20, 2019

Status Verified

February 1, 2019

Enrollment Period

3 months

First QC Date

February 24, 2017

Last Update Submit

February 19, 2019

Conditions

Outcome Measures

Primary Outcomes (1)

  • Colonoscopy participation

    The percent of participants who complete screening colonoscopy

    3 months

Secondary Outcomes (2)

  • Colonoscopy scheduling

    3 months

  • Risk assessment completion

    3 months

Study Arms (2)

No incentive

ACTIVE COMPARATOR

Colon cancer risk assessment and direct access colonoscopy scheduling for those that are eligible.

Behavioral: No incentive

Incentive

EXPERIMENTAL

Loss-framed incentive to participate in risk assessment and additional unconditional pro-social incentive to complete colorectal cancer screening.

Behavioral: Incentive

Interventions

No incentiveBEHAVIORAL

Each participant will receive an email describing the importance of colorectal cancer screening and that they have been selected to receive a risk assessment. They will directed to an online platform where they will be asked about age, family history, and prior screening history. Those who are eligible for screening will be offered the VIP access phone number to schedule an appointment.

No incentive
IncentiveBEHAVIORAL

Each participant will receive an email describing the importance of colorectal cancer screening and that they have been selected to receive a risk assessment, for which they will received a loss-framed incentive. They will directed to an online platform where they will be asked about age, family history, and prior screening history. Those who are eligible for screening will be offered the VIP access phone number to schedule an appointment and will receive an additional unconditional pro-social incentive.

Incentive

Eligibility Criteria

Age50 Years - 64 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • male and female UPHS employees between the ages 50-64
  • those who live within 30 miles of the main endoscopy sites

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Pennsylvania Health System

Philadelphia, Pennsylvania, 19104, United States

Location

Related Publications (1)

  • Mehta SJ, Reitz C, Niewood T, Volpp KG, Asch DA. Effect of Behavioral Economic Incentives for Colorectal Cancer Screening in a Randomized Trial. Clin Gastroenterol Hepatol. 2021 Aug;19(8):1635-1641.e1. doi: 10.1016/j.cgh.2020.06.047. Epub 2020 Jul 2.

MeSH Terms

Conditions

Colonic Neoplasms

Condition Hierarchy (Ancestors)

Colorectal NeoplasmsIntestinal NeoplasmsGastrointestinal NeoplasmsDigestive System NeoplasmsNeoplasms by SiteNeoplasmsDigestive System DiseasesGastrointestinal DiseasesColonic DiseasesIntestinal Diseases

Study Officials

  • Shivan Mehta, MD

    University of Pennsylvania

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
INVESTIGATOR
Purpose
SCREENING
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Professor of Medicine

Study Record Dates

First Submitted

February 24, 2017

First Posted

March 1, 2017

Study Start

May 8, 2017

Primary Completion

August 8, 2017

Study Completion

November 8, 2017

Last Updated

February 20, 2019

Record last verified: 2019-02

Data Sharing

IPD Sharing
Will not share

Locations