Examining Benefits of Modified Cogmed Training With ADHD at Cambridge Memorial Hospital(CMH)

NCT02610244 | Terminated DMC

• 3 other identifiers: ADHD-MCT-090920152015-056320679
• Study Type: interventional
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

ADHD youth (8-16 years) will be randomized to either treatment-as-usual group or a modified version of the Cogmed program (MCT) that is suitable for use in a hospital setting (duration = 3 daily 35-min sessions for 10 weeks). The main objectives are to determine whether there is improvement in working memory and attention, a reduction in concerns related to ADHD and social emotional behaviour,and transfer effects for reading and math following participation in our MCT.

Conditions

Attention Deficit Hyperactivity Disorder

Outcome Measures

Primary Outcomes (5)

• Changes assessed for Working Memory Index (BRIEF measure) and working memory (verbal and Visual-spatial) as measured on Alloway Working Memory Test

  The BRIEF Parent/Teacher ratings of youth's working memory index and Youth 's scores on Alloway Working Memory test at baseline will be compared with scores after 10 weeks modified cogmed training or treament-as-usual, and after 3 months

  Baseline,10 weeks, 3 months

• Changes assessed on Beck Self-Concept

  Self-concept measures will be compared from baseline to after completing Cogmed training and at 3 month follow up.

  Baseline,10 weeks, 3 months

• Change assessed on Tova Attention Performance Index

  Attention Performance Index measures will be compared from baseline to after completing Cogmed training and at 3 month follow up.

  Baseline,10 weeks, 3 months

• Change assessed on Wiat-111 Reading comprehension and math problem-solving

  Reading Comprehension and Math problem-solving measures will be compared from baseline to after completing Cogmed training and at 3 month follow up.

  Baseline,10 weeks, 3 months

• Change assessed on Achenbach Reduction in Total Problems Scale

  Total Problem scale measures will be compared from baseline to after completing Cogmed training and at 3 month follow up.

  Baseline,10 weeks, 3 months

Study Arms (2)

Treatment As Usual

NO INTERVENTION

Standard treatment as usual as directed by the physician.

Modified Cogmed Training

EXPERIMENTAL

10 weeks of computerized training (3x weekly for 35-minutes each session) that targets thinking skills that are often impaired in individuals diagnosed with ADHD.

Other: Modified Cogmed Training

Interventions

Modified Cogmed Training OTHER

Comparison of outcome measures between treatment-as-usual group and Modified Cogmed Training group after 10 weeks and 3 months follow up.

Modified Cogmed Training

Eligibility Criteria

• Age: 8 Years - 16 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17)

You may qualify if:

• Youth who are between 8-16 years age.
• Youth with a primary diagnosis of ADHD per psychiatric and psychological assessment.
• Youth with an estimated Intelligence Quotient (IQ) equal or greater than 80 on an intelligence measure (Wechsler Abbreviated Scale of Intelligence; WASI), where the average IQ varies from 90-110.
• Youth with reading comprehension at or above a grade 2 level on a standardized reading test (Wechsler Individual Achievement Test - 3rd Edition; WIAT-III).
• Youth who are receiving medication will have made an adequate adjustment to their medication as shown by stable blood levels, psychiatric consultation, and self and parent report at least 2 weeks prior to the start of their acceptance into this study.

You may not qualify if:

• Youth who are younger than 8 or older than 16 at the time of enrollment.
• Youth who do not have a primary diagnosis of ADHD.
• Youth with an estimated Intelligence Quotient (IQ) below 80 on an intelligence measure (Wechsler Abbreviated Scale of Intelligence; WASI), where the average IQ varies from 90-110. Children with intellectual functioning below this level have been found to have trouble following instructions that are necessary for the training program.
• Youth with reading comprehension below a grade 2 level on a standardized reading test (Wechsler Individual Achievement Test - 3rd Edition; WIAT-III). Children with reading skills below this level have been found to have trouble following instructions that are necessary for the training program.
• Youth do not intend to begin new medication, discontinue existing medication, or change dose in medication - unless indicated per their doctor's instructions - for the duration of their involvement in the study.
• Youth cannot be accepted into the study if they have a significant medical impairment that would preclude their participation, a significant uncorrected visual/hearing deficit that would make it difficult for them to see a computer screen and follow verbal instructions, and/or a significant problem with their fine motor control that would make it difficult for them to use a keyboard.

Sponsors & Collaborators

• Cambridge Memorial Hospital: lead
• University of Waterloo: collaborator

Study Sites (1)

Outpatient Mental Health,

Cambridge, Ontario, N1R 3G2, Canada

Location

MeSH Terms

Conditions

Attention Deficit Disorder with Hyperactivity

Condition Hierarchy (Ancestors)

Attention Deficit and Disruptive Behavior Disorders; Neurodevelopmental Disorders; Mental Disorders

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: November 12, 2015
• First Posted: November 20, 2015
• Study Start: November 1, 2015
• Primary Completion: December 1, 2019
• Study Completion: December 1, 2019
• Last Updated: January 23, 2020

Record last verified: 2020-01

Locations

CA (1)