Computerized Decision Support System Linked to Electronic Health Records to Improve Patient Care in a General Hospital
CODES
Implementing an Evidence-based Computerized Decision Support System Linked to Electronic Health Records to Improve Patient Care in a General Hospital
1 other identifier
interventional
6,479
1 country
1
Brief Summary
Computerized decision support systems (CDSSs) are information technology-based software that provide health professionals with actionable, patient-specific recommendations or guidelines for disease diagnosis, treatment, and management at the point-of-care. CDSSs may be integrated with patient electronic health records (EHRs) and evidence-based knowledge.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable
Started Nov 2015
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
October 14, 2015
CompletedFirst Posted
Study publicly available on registry
October 16, 2015
CompletedStudy Start
First participant enrolled
November 1, 2015
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 1, 2016
CompletedStudy Completion
Last participant's last visit for all outcomes
January 1, 2017
CompletedJanuary 30, 2017
October 1, 2016
1.1 years
October 14, 2015
January 27, 2017
Conditions
Outcome Measures
Primary Outcomes (1)
Resolution rates
Rate at which the medical problems, which are detected by the MediDSS software and reported through the reminders, are resolved (resolution rates).
12 months
Secondary Outcomes (2)
in-hospital mortality
12 months
length of hospital stay
12 months
Study Arms (2)
Intervention
EXPERIMENTALElectronic Health Records with computerised decision support system activated Medilogy Decision Support System (MediDSS)
Control
OTHERElectronic Health Records with computerised decision support system silenced Medilogy Decision Support System (MediDSS) silenced
Interventions
Italian translation of Evidence-Based Medicine electronic Decision Support (EBMeDS), a set of rules (scripts) based on Evidence Based Medicine guidelines and applied to structured health data. MediDSS further includes knowledge from Swedish, Finnish, INteraction X-referencing (SFINX), a drug-drug interaction database containing concise evidence-based information of about 18,000 drug interactions and adverse events. MediDSS is integrated with local reminders.
Eligibility Criteria
You may qualify if:
- All of the patients admitted into the internal medicine departments of the Azienda Ospedaliera di Desio e Vimercate during the study period.
You may not qualify if:
- None
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogiolead
- University of Milancollaborator
Study Sites (1)
Ospedale di Vimercate
Vimercate, Lombardy, Italy
Related Publications (5)
Moja L, Kwag KH, Lytras T, Bertizzolo L, Brandt L, Pecoraro V, Rigon G, Vaona A, Ruggiero F, Mangia M, Iorio A, Kunnamo I, Bonovas S. Effectiveness of computerized decision support systems linked to electronic health records: a systematic review and meta-analysis. Am J Public Health. 2014 Dec;104(12):e12-22. doi: 10.2105/AJPH.2014.302164. Epub 2014 Oct 16.
PMID: 25322302BACKGROUNDMoja L, Liberati EG, Galuppo L, Gorli M, Maraldi M, Nanni O, Rigon G, Ruggieri P, Ruggiero F, Scaratti G, Vaona A, Kwag KH. Barriers and facilitators to the uptake of computerized clinical decision support systems in specialty hospitals: protocol for a qualitative cross-sectional study. Implement Sci. 2014 Aug 28;9:105. doi: 10.1186/s13012-014-0105-0.
PMID: 25163794BACKGROUNDLiberati EG, Galuppo L, Gorli M, Maraldi M, Ruggiero F, Capobussi M, Banzi R, Kwag K, Scaratti G, Nanni O, Ruggieri P, Polo Friz H, Cimminiello C, Bosio M, Mangia M, Moja L. [Barriers and facilitators to the implementation of computerized decision support systems in Italian hospitals: a grounded theory study]. Recenti Prog Med. 2015 Apr;106(4):180-91. doi: 10.1701/1830.20032. Italian.
PMID: 25959891BACKGROUNDMoja L, Polo Friz H, Capobussi M, Kwag K, Banzi R, Ruggiero F, Gonzalez-Lorenzo M, Liberati EG, Mangia M, Nyberg P, Kunnamo I, Cimminiello C, Vighi G, Grimshaw J, Bonovas S. Implementing an evidence-based computerized decision support system to improve patient care in a general hospital: the CODES study protocol for a randomized controlled trial. Implement Sci. 2016 Jul 7;11(1):89. doi: 10.1186/s13012-016-0455-x.
PMID: 27389248BACKGROUNDMoja L, Polo Friz H, Capobussi M, Kwag K, Banzi R, Ruggiero F, Gonzalez-Lorenzo M, Liberati EG, Mangia M, Nyberg P, Kunnamo I, Cimminiello C, Vighi G, Grimshaw JM, Delgrossi G, Bonovas S. Effectiveness of a Hospital-Based Computerized Decision Support System on Clinician Recommendations and Patient Outcomes: A Randomized Clinical Trial. JAMA Netw Open. 2019 Dec 2;2(12):e1917094. doi: 10.1001/jamanetworkopen.2019.17094.
PMID: 31825499DERIVED
Study Officials
- PRINCIPAL INVESTIGATOR
Pasquale Lorenzo Moja, MD, PhD
Unità di Epidemiologia Clinica, IRCCS Istituto Ortopedico Galeazzi, Milano
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- OUTCOMES ASSESSOR
- Purpose
- HEALTH SERVICES RESEARCH
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
October 14, 2015
First Posted
October 16, 2015
Study Start
November 1, 2015
Primary Completion
December 1, 2016
Study Completion
January 1, 2017
Last Updated
January 30, 2017
Record last verified: 2016-10