The PROspective German NOn-CF bronchiectaSIS Patient Registry
PROGNOSIS
1 other identifier
observational
750
1 country
19
Brief Summary
The purpose of this study is to study the epidemiology of non-CF bronchiectasis (NCFB) and to provide an estimate of the distribution (prevalence) of NCFB etiologies across all different levels of health care as well as real-life data regarding the current management of NCFB in Germany.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Jul 2015
Longer than P75 for all trials
19 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
July 1, 2015
CompletedFirst Submitted
Initial submission to the registry
July 17, 2015
CompletedFirst Posted
Study publicly available on registry
October 12, 2015
CompletedPrimary Completion
Last participant's last visit for primary outcome
November 1, 2020
CompletedStudy Completion
Last participant's last visit for all outcomes
July 1, 2021
CompletedOctober 27, 2020
October 1, 2020
5.3 years
July 17, 2015
October 26, 2020
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Number of participants with non-CF bronchiectasis (NCFB) across all different levels of health care regarding the current management of NCFB in Germany
To establish a national, representative, prospective, observational and longitudinal NCFB database and collaborative research network with a database including a minimum of 750 patients from a minimum of 25 centers from all levels of healthcare across Germany after a period of 3 years.
three years
Secondary Outcomes (1)
Prevalence of non-CF bronchiectasis (NCFB) etiologies (composite outcome measures) across all different levels of health care
three years
Eligibility Criteria
Patients with non-CF bronchiectasis
You may qualify if:
- A clinical history consistent with bronchiectasis
- (High resolution) computed tomography (CT) scan of the chest demonstrating bronchiectasis affecting 1 or more lobes
You may not qualify if:
- Bronchiectasis due to known cystic fibrosis (CF)
- Age \<18 years
- Interstitial lung disease
- Prior lung or heart-lung transplantation
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Hannover Medical Schoollead
- CAPNETZ Stiftungcollaborator
- German Center for Lung Researchcollaborator
Study Sites (19)
Helios Klinikum Emil von Behring - Lungenklinik Heckeshorn
Berlin, Germany
Augusta-Kranken-Anstalt Bochum -Klinik für Pneumologie, Beatmungsmedizin und Infektiologie
Bochum, Germany
Fachkrankenhaus Coswig
Coswig, Germany
Klinik Donaustauf - Zentrum für Pneumologie
Donaustauf, Germany
Klinikum Dortmund Medizinische Klinik Nord - Pneumologie, Infektiologie und Internistische Intensivmedizin
Dortmund, Germany
Universitätsklinikum Carl Gustav Carus an der TU Dresden Medizinische Klinik und Poliklinik I, Bereich Pulmologie
Dresden, Germany
Florence-Nightingale-Krankenhaus Klinik für Pneumologie, Allergologie, Schlaf- und Beatmungsmedizin
Düsseldorf, Germany
Praxis am Maingau Krankenhaus Gemeinschaftspraxis für Innere Medizin, Lungen- und Bronchialheilkunde, Allergologie
Frankfurt, Germany
Universitätsklinikum Freiburg Abteilung für Klinische Infektiologie
Freiburg im Breisgau, Germany
UKGM - Standort Gießen Medizinische Klinik und Poliklinik II
Giessen, Germany
LungenClinic Großhansdorf
Großhansdorf, Germany
Medizinische Hochschule Hannover-Klinik für Pneumologie
Hanover, Germany
Universitätsklinikum Heidelberg und Thoraxklinik Heidelberg
Heidelberg, Germany
Universitätsklinikum Jena Zentrum für Infektionsmedizin und Krankenhaushygiene
Jena, Germany
Universitätsklinikum Schleswig-Holstein Medizinische Klinik III - Pneumologie / Infektiologie
Lübeck, Germany
Klinikum Lüdenscheid Klinik für Pneumologie, Infektiologie, Schlafmedizin und Internistische Intensivmedizin
Lüdenscheid, Germany
Klinikum der Philipps-University Marburg
Marburg, Germany
Klinikum der Ludwig-Maximilians-Universität München
München, Germany
Diakoniekrankenhaus Rotenburg Zentrum für Pneumologie
Rotenburg (Wümme), Germany
Related Publications (1)
Ewen R, Pink I, Sutharsan S, Aries SP, Grunewaldt A, Shoemark A, Sommerwerck U, Staar BO, Wege S, Mertsch P, Rademacher J, Ringshausen FC; PROGNOSIS Study Group. Primary Ciliary Dyskinesia in Adult Bronchiectasis: Data from the German Bronchiectasis Registry PROGNOSIS. Chest. 2024 Nov;166(5):938-950. doi: 10.1016/j.chest.2024.05.023. Epub 2024 Jun 15.
PMID: 38880279DERIVED
Related Links
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- STUDY CHAIR
Jessica Rademacher
CAPNETZ STIFTUNG; Medizinische Hochschule Hannover
- STUDY CHAIR
Felix C. Ringshausen
CAPNETZ STIFTUNG; Medizinische Hochschule Hannover
- STUDY CHAIR
Andrés de Roux
Pneumologische Praxis Berlin
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- CASE ONLY
- Time Perspective
- PROSPECTIVE
- Target Duration
- 3 Years
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
July 17, 2015
First Posted
October 12, 2015
Study Start
July 1, 2015
Primary Completion
November 1, 2020
Study Completion
July 1, 2021
Last Updated
October 27, 2020
Record last verified: 2020-10