Comparison of Physical Activity Level Between Patients With Bronchiectasis and Healthy Subjects

NCT02550821 | Completed

• 1 other identifier: GO 15/313
• Study Type: observational
• Target: 76
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is to compare physical activity levels between patients with bronchiectasis and healthy subjects. We hypothesize that patients with bronchiectasis will have lower levels of physical activity, since physical activity levels is affected by reduced exercise tolerance, severity of disease and other disease related symptoms and conditions.

Conditions

Bronchiectasis

Keywords

Physical activity levels; Bronchiectasis

Outcome Measures

Primary Outcomes (4)

• Number of steps on accelerometer

  Participants will wear an accelerometer (physical activity monitor) for seven consecutive days.

  Seven days

• Energy expenditure on activity monitor

  Total energy expenditure will be calculated using activity monitor for seven consecutive days

  Seven days

• Exercise capacity using 6-minute walk test and incremental shuttle walk test

  6-minute walk test will be performed in a long, straight, enclosed corridor 30 meters in length. Patients are required to walk in their walking speed with standardized instructions. The distance walked by subjects during 6 minutes will be recorded. The incremental shuttle walk test will be performed in an enclosed corridor. Patients are required to walk back and forth, turning around two cones placed 9 meters apart making the shuttle distance 10 meters long. Patients will follow the rhythm dictated by the audio signal.

  8th day (after using device)

• Physical activity level using International Physical Activity Questionnaire

  Instrument to obtain internationally comparable data on health related physical activity This measure assesses the types of intensity of physical activity and sitting time in daily life and estimates total physical activity in MET-min/week and time spent sitting. It comprises open-ended questions surrounding individuals' last 7-day recall of physical activity.

  8th day

Secondary Outcomes (4)

• Shortness of breath using the Modified Medical Research Council Dyspnea Scale

  1st day (before using device)

• Quality of Life using St. George Respiratory Questionnaire

  1st day

• Peripheral muscle strength test using a hand-held dynamometer

  8th day (after using device)

• Maximal inspiratory and expiratory pressures measurement using a mouthpiece device

  8th day (after using device)

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

The study population will consist of patients with bronchiectasis and healthy subjects.

You may qualify if:

• Diagnosis of bronchiectasis
• Being 18 years of age or older
• Able and willing to complete the informed consent process.
• Able to walk and co-operate

You may not qualify if:

• Unstable medical condition
• To have severe neurological, orthopedic problems or severe heart failure.
• The control group will consist of healthy subjects.

Sponsors & Collaborators

• Hacettepe University: lead

Study Sites (1)

Aslihan Cakmak

Ankara, 06100, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Bronchiectasis

Condition Hierarchy (Ancestors)

Bronchial Diseases; Respiratory Tract Diseases

Study Officials

• ASLIHAN CAKMAK

  Hacettepe University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Research Assistant

Study Record Dates

• First Submitted: September 13, 2015
• First Posted: September 16, 2015
• Study Start: September 1, 2015
• Primary Completion: August 1, 2016
• Study Completion: August 1, 2016
• Last Updated: September 9, 2019

Record last verified: 2019-09

Locations

TU (1)