NCT07104942

Brief Summary

This study investigates the relationship between expiratory muscle strength and clinical outcomes such as disease severity, hospital admissions, and quality of life in individuals with bronchiectasis.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
64

participants targeted

Target at P25-P50 for all trials

Timeline
0mo left

Started Aug 2025

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress97%
Aug 2025Jun 2026

First Submitted

Initial submission to the registry

July 22, 2025

Completed
10 days until next milestone

Study Start

First participant enrolled

August 1, 2025

Completed
4 days until next milestone

First Posted

Study publicly available on registry

August 5, 2025

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2025

Completed
6 months until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2026

Expected
Last Updated

August 24, 2025

Status Verified

August 1, 2025

Enrollment Period

4 months

First QC Date

July 22, 2025

Last Update Submit

August 22, 2025

Conditions

Bronchiectasis

Keywords

BronchiectasisExpiratory muscle strength

Outcome Measures

Primary Outcomes (1)

  • Respiratory Muscle Strength

    Respiratory muscle function will be assessed by measuring maximal inspiratory pressure (MIP) and maximal expiratory pressure (MEP) in the sitting position using a mouth pressure device (MEC PFT Systems Pocket-Spiro).

    Baseline

Secondary Outcomes (8)

  • Modified Medical Research Council Dyspnea Score

    Baseline

  • Leicester Cough Questionnaire

    Baseline

  • Bronchiectasis Severity Index

    Baseline

  • Hospital Anxiety Depression Scale

    Baseline

  • Fatigue severity scale

    Baseline

  • +3 more secondary outcomes

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Süreyyapaşa Chest Diseases and Chest Surgery Training and Research Hospital

You may qualify if:

  • Having a diagnosis of non-cystic fibrosis bronchiectasis
  • Without an acute infection at the time of assessment (confirmed by medical history, serum C-reactive protein levels, chest X-ray and/or HRCT).
  • Being between 18 and 65 years of age

You may not qualify if:

  • Myopathies
  • Stroke (Cerebrovascular accident - CVA)
  • Pregnancy
  • Unstable cardiac disease

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Süreyyapaşa Chest Diseases and Chest Surgery Training and Research Hospital

Istanbul, Turkey (Türkiye)

RECRUITING

MeSH Terms

Conditions

Bronchiectasis

Condition Hierarchy (Ancestors)

Bronchial DiseasesRespiratory Tract Diseases

Central Study Contacts

Nisanur Tutuş

CONTACT

(0216) 421 42 00nisanurtutuss@gmail.com

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

July 22, 2025

First Posted

August 5, 2025

Study Start

August 1, 2025

Primary Completion

December 1, 2025

Study Completion (Estimated)

June 1, 2026

Last Updated

August 24, 2025

Record last verified: 2025-08

Locations

TU(1)