Hypercapnia and Gas Exchange Under the Avalanche Snow Model (HyperAvaSM)

NCT02521272 | Completed

• 1 other identifier: VentRes-2015-01-KR
• Study Type: interventional
• Target: 12
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of the study is to investigate respiratory parameters of a person in the simulated avalanche snow and consequent use of the measured data for development of a mathematical-physical model of breathing during increasing hypercapnia in the avalanche.

Conditions

Accident Caused by Snow Avalanche

Outcome Measures

Primary Outcomes (1)

• The length of breathing

  Time to termination of the breathing experiment due to the decision of the subject, or determined by high End-Tidal CO2 value or by the order by the clinician assessing the health status of the subjects.

  Continuously within 30 minute interval from the beginning of the breathing experiment

Study Arms (1)

air pocket

EXPERIMENTAL

Breathing in the simulated avalanche snow.

Other: Breathing in the simulated avalanche snow.; Device: air pocket

Interventions

Breathing in the simulated avalanche snow. OTHER

Breathing in the simulated avalanche snow with zero air pocket and one-liter air pocket.

air pocket

air pocket DEVICE

Zero air pocket or one-liter air pocket in the snow.

air pocket

Eligibility Criteria

• Age: 20 Years - 30 Years
• Sex: male
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Participants were volunteers from the Czech Army forces, studying at the Military Department of the Faculty of Physical Education and Sport, Charles University in Prague. All subjects were healthy and fit, classified as ASA I, all without a smoking history. The volunteers were highly motivated to participate in the experiment. The entrance examination, completed before the start of the study, included these tests: electrocardiography, blood pressure, spirometry, and assessment of the health conditions and family anamnesis by a physician with a specialty in anesthesia and critical care.

Sponsors & Collaborators

• Czech Technical University in Prague: lead
• Charles University, Czech Republic: collaborator

Study Sites (1)

Charles University, Czech Republic

Prague, 162 00, Czechia

Location

Related Publications (3)

• Brugger H, Sumann G, Meister R, Adler-Kastner L, Mair P, Gunga HC, Schobersberger W, Falk M. Hypoxia and hypercapnia during respiration into an artificial air pocket in snow: implications for avalanche survival. Resuscitation. 2003 Jul;58(1):81-8. doi: 10.1016/s0300-9572(03)00113-8.

  PMID: 12867313 BACKGROUND

• Bellani G, Patroniti N, Weismann D, Galbiati L, Curto F, Foti G, Pesenti A. Measurement of pressure-time product during spontaneous assisted breathing by rapid interrupter technique. Anesthesiology. 2007 Mar;106(3):484-90. doi: 10.1097/00000542-200703000-00012.

  PMID: 17325506 BACKGROUND

• Grissom CK, Radwin MI, Harmston CH, Hirshberg EL, Crowley TJ. Respiration during snow burial using an artificial air pocket. JAMA. 2000 May 3;283(17):2266-71. doi: 10.1001/jama.283.17.2266.

  PMID: 10807386 BACKGROUND

MeSH Terms

Interventions

Respiration

Intervention Hierarchy (Ancestors)

Respiratory Physiological Phenomena; Circulatory and Respiratory Physiological Phenomena

Study Officials

• Karel Roubik, prof., Ph.D.

  Czech Technical University in Prague

  STUDY DIRECTOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: DOUBLE
• Who Masked: PARTICIPANT, INVESTIGATOR
• Purpose: BASIC SCIENCE
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: August 10, 2015
• First Posted: August 13, 2015
• Study Start: March 1, 2012
• Primary Completion: March 1, 2012
• Study Completion: March 1, 2012
• Last Updated: August 13, 2015

Record last verified: 2015-08

Locations

CZ (1)