Antioxidant and Anti-inflammatory Effects of Yogurt Enriched With Polyphenols
Investigation of the Antioxidant and Anti-inflammatory Effects of Yogurt Enriched With Polyphenols
1 other identifier
interventional
18
1 country
1
Brief Summary
The purpose of this study is to investigate the possible antioxidant and anti-inflammatory effects of yogurt enriched with polyphenols after 2-week consumption by healthy individuals.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable
Started May 2015
Shorter than P25 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
May 1, 2015
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 1, 2015
CompletedStudy Completion
Last participant's last visit for all outcomes
June 1, 2015
CompletedFirst Submitted
Initial submission to the registry
June 25, 2015
CompletedFirst Posted
Study publicly available on registry
July 10, 2015
CompletedFebruary 2, 2016
January 1, 2016
1 month
June 25, 2015
January 31, 2016
Conditions
Keywords
Outcome Measures
Primary Outcomes (2)
Antioxidant effects
Indices of blood antioxidant status
Two weeks
Anti-inflammatory effects
Indices of inflammation in blood
Two weeks
Secondary Outcomes (8)
Body composition
Two weeks
Blood pressure
Two weeks
Hydration
Two weeks
Resting heart rate
Two weeks
Blood glucose levels
Two weeks
- +3 more secondary outcomes
Study Arms (2)
Yogurt enriched with polyphenols
EXPERIMENTALTwo yogurts (400g) enriched with polyphenols (10mg/100g yogurt) per day, for two weeks.
Yogurt not enriched with polyphenols
PLACEBO COMPARATORTwo yogurts (400g) not enriched with polyphenols per day, for two weeks.
Interventions
Yogurt enriched with polyphenols extracted from grape seeds
Yogurt not enriched with polyphenols
Eligibility Criteria
You may qualify if:
- Healthy individuals
- Non-smokers
You may not qualify if:
- Current use of dietary supplements or drugs
- Metabolic disease
- Lactose intolerance
- Pregnant, pregnancy intention or breast feeding
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Department of Physical Education & Sport Science of the University of Thessaly
Trikala, Karyes, 42100, Greece
Related Publications (2)
Najgebauer-Lejko D, Grega T, Tabaszewska M. Yoghurts with addition of selected vegetables: acidity, antioxidant properties and sensory quality. Acta Sci Pol Technol Aliment. 2014 Jan-Mar;13(1):35-42. doi: 10.17306/j.afs.2014.1.3.
PMID: 24583382BACKGROUNDLamothe S, Azimy N, Bazinet L, Couillard C, Britten M. Interaction of green tea polyphenols with dairy matrices in a simulated gastrointestinal environment. Food Funct. 2014 Oct;5(10):2621-31. doi: 10.1039/c4fo00203b. Epub 2014 Aug 26.
PMID: 25154916BACKGROUND
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- STUDY DIRECTOR
Athanasios Z Jamurtas, PhD
University of Thessaly
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- TRIPLE
- Who Masked
- PARTICIPANT, CARE PROVIDER, INVESTIGATOR
- Purpose
- BASIC SCIENCE
- Intervention Model
- CROSSOVER
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Associate Professor
Study Record Dates
First Submitted
June 25, 2015
First Posted
July 10, 2015
Study Start
May 1, 2015
Primary Completion
June 1, 2015
Study Completion
June 1, 2015
Last Updated
February 2, 2016
Record last verified: 2016-01
Data Sharing
- IPD Sharing
- Will not share