Cognitive Dysfunction in COPD Patients : Role in the Performance of Cognitive-motor Dual Task Situation?

NCT02493790 | Completed

• 1 other identifier: 5S-DYSCO
• Study Type: observational
• Target: 45
• Locations: 0 countries
• Sites: N/A

Brief Summary

Chronic Obstructive Pulmonary Disease (COPD) is a respiratory disease starting point characterized by multiple systemic effects as cognitive dysfunction. This one seems to have an impact in activity daily living, considered mainly as a cognitive-motor dual task situations. Yet to date, no study has specifically focused in the cognitive-motor performance in patients with COPD or on the effects during a rehabilitation program. The main objective of this work was to evaluate the impact of cognitive dysfunction in COPD, comparing performance between COPD patients and healthy subjects in a single and dual task cognitive-motor situation. The secondary objective was to assess the impact of a rehabilitation program on these performances.

Conditions

Chronic Obstructive Pulmonary Disease

Keywords

cognitive dysfunction; Activity of Daily Living; interference; rehabilitation; cognitive-motor dual task

Outcome Measures

Primary Outcomes (2)

• Variability of Cognitive performances in a single and dual task situations

  Cognitive performance were determined by error count and number of substraction during a counting task.

  3 months

• Variability of motor performances in a single and dual task situations

  Motor performance were determined by variability of length and surface of postural condition and by step variability in locomotion condition

  3 months

Secondary Outcomes (2)

• Effect of rehabilitation program on Cognitive performances in a single and dual task

  3 months

• Effect of rehabilitation program on motor performances in a single and dual task

  3 months

Study Arms (2)

Volunteers

Cognitive and motor performances were measured in a single and dual task situations.

Other: Cognitive and motor performances

COPD patients

Cognitive and motor performances were measured in a single and dual task situations, before rehabilitation, and compared to those of healthy subjects. Then, Chronic Obstructive Pulmonary Disease patients were re-evaluated after rehabilitation.

Other: Cognitive and motor performances

Interventions

Cognitive and motor performances OTHER

COPD patients; Volunteers

Eligibility Criteria

• Age: 40 Years - 80 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

COPD patients, entered in a rehabilitation program in Clinique du Souffle were included

You may qualify if:

• Male or female about 40 to 80 years old
• COPD patient (Tiffeneau \<70%); stage moderate to severe (Stage 2,3 and 4) with or without oxygen therapy (\>15h/day)
• Written and informed consent of the subject
• Authorization to physical activity referring doctor in the clinic
• Comorbidities no dominating

You may not qualify if:

• Subject with neurological pathology, cognitive or psychiatric
• Subject with pain and / or plantar injuries
• Subject has a prosthetic knee and / or hip.
• Subject requiring walking aid (cane, walker, etc.)

Sponsors & Collaborators

• 5 Santé: lead
• Groupe 5 Santé: collaborator

MeSH Terms

Conditions

Pulmonary Disease, Chronic Obstructive; Cognitive Dysfunction

Condition Hierarchy (Ancestors)

Lung Diseases, Obstructive; Lung Diseases; Respiratory Tract Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Cognition Disorders; Neurocognitive Disorders; Mental Disorders

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 30, 2015
• First Posted: July 10, 2015
• Study Start: October 1, 2014
• Primary Completion: June 1, 2015
• Study Completion: August 1, 2016
• Last Updated: December 20, 2016

Record last verified: 2016-12