DesCoM-1
Phase 1 Impact of Nocturnal Desaturations on Central Motor Drive in COPD Patients: A New Insight on the Systemic Effects of the Disease.
Sponsor study identifier
observational
137
1 country
1
Study Start
July 2012
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
April 2014
Actual (reported)Study Completion
April 2014
Actual (reported)The purpose of this study is to determine whether nervous system alterations and motor drive failure can contribute to muscle weakness in COPD during voluntary movement. If necessary, we will look after the role of nocturnal hypoxia in these alterations.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
April 2014
Actual (reported)Click on a node to explore related trials.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
July 2012
Date type not reportedThis date has not been verified as actual or estimated.
September 3, 2012
Actual (reported)September 6, 2012
Actual (reported)April 2014
Actual (reported)April 2014
Actual (reported)Level of voluntary activation
2h
COPD patients who spend 30% of the nigth with a SaO2 \< 90%.
COPD patients who spend less than 30% of the night with a SaO2 \< 90%
healthy sedentary subjects
Two groups of COPD patients and one group with healthy sedentary subjects
Clinique du Souffle La Vallonie
Lodève, 34700, France
Alexandre F, Heraud N, Sanchez AM, Tremey E, Oliver N, Guerin P, Varray A. Brain Damage and Motor Cortex Impairment in Chronic Obstructive Pulmonary Disease: Implication of Nonrapid Eye Movement Sleep Desaturation. Sleep. 2016 Feb 1;39(2):327-35. doi: 10.5665/sleep.5438.
whole blood
Alain AV Varray, Pr
M2H laboratory, Montpellier
137 participants (actual enrollment reported by the registry).
First Submitted
September 3, 2012
First Posted
September 6, 2012
Study Start
July 2012
Date type not reportedThis date has not been verified as actual or estimated.
Asymptomatic Versus Symptomatic Mild COPD: Comparisons at Rest and at Exercise
Contact the study team to confirm eligibility.
Primary Completion
April 2014
Actual (reported)Study Completion
April 2014
Actual (reported)Last Updated
March 10, 2015
Record last verified: 2015-03
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Source: ClinicalTrials.gov.
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