NCT02490137

Brief Summary

The purpose is to use MRI to investigate brain changes associated with playing a race car video game for 90 minutes in aging adults both with and without early signs of dementia.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
20

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Jun 2015

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 15, 2015

Completed
16 days until next milestone

First Submitted

Initial submission to the registry

July 1, 2015

Completed
2 days until next milestone

First Posted

Study publicly available on registry

July 3, 2015

Completed
2.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 15, 2017

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 15, 2017

Completed
Last Updated

January 10, 2019

Status Verified

January 1, 2019

Enrollment Period

2.2 years

First QC Date

July 1, 2015

Last Update Submit

January 8, 2019

Conditions

AgingDementia

Outcome Measures

Primary Outcomes (1)

  • MRI: Mean Diffusivity

    MRI based Mean Diffusivity changes in brain following playing video game for 90 minutes

    1.5-2 hours

Secondary Outcomes (1)

  • MRI: Structural Morphometry

    1.5-2 hours

Study Arms (2)

Game Players

EXPERIMENTAL

Participants that will play video game

Behavioral: Race Car Video Game

Control

NO INTERVENTION

No video game experience

Interventions

Race Car Video GameBEHAVIORAL

Repeatedly playing a race car video game

Game Players

Eligibility Criteria

Age50 Years - 80 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • years of age
  • Part of existing aging research sample cohorts at University of Wisconsin - Madison
  • Successful research MRI study within prior two years
  • May include participants with
  • No diagnosed cognitive impairment
  • amnestic MCI
  • mild AD (single or multi-domain) with predominant amnesia

You may not qualify if:

  • Contraindications to MRI (see Risks of MRI below)
  • Significant experience with playing race car video games in previous 2 years.
  • Severe AD
  • Lack of capacity as determined by the Capacity Assessment of Understanding questionnaire
  • Women who may be pregnant

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Wisconsin - Madison

Madison, Wisconsin, 53705, United States

Location

MeSH Terms

Conditions

Dementia

Condition Hierarchy (Ancestors)

Brain DiseasesCentral Nervous System DiseasesNervous System DiseasesNeurocognitive DisordersMental Disorders

Study Officials

  • Andrew Alexander, Ph.D.

    University of Wisconsin, Madison

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
BASIC SCIENCE
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 1, 2015

First Posted

July 3, 2015

Study Start

June 15, 2015

Primary Completion

August 15, 2017

Study Completion

August 15, 2017

Last Updated

January 10, 2019

Record last verified: 2019-01

Locations

US(1)