Circulatory Levels of Irisin in Response to Acute Resistance Training

NCT02478658 | Completed

• 1 other identifier: 504792A
• Study Type: interventional
• Target: 28
• Locations: 1 country
• Sites: 1

Brief Summary

Study the circulatory levels of irisin in response to one session of high-intensity resistance training in a group of healthy subjects.

Conditions

Healthy

Keywords

irisin; resistance training; physical fitness; Volunteers

Outcome Measures

Primary Outcomes (1)

• Serum irisin levels

  Changes in irisin levels baseline, 45 min (during the training session), and post-training session

  1 day

Secondary Outcomes (7)

• Body composition assessment, as measured by DEXA and anthropometry

  1 day

• Lactate levels

  1 day

• Physical Fitness levels as measured by 1 RM (repetition maximum) and Cardio-respiratory maximal test

  1day

• Blood Glucose levels

  1 session (1 day)

• Diet assessment: 24 hour recall and Food Preference Questionnaire

  1day

Study Arms (2)

Intervention

EXPERIMENTAL

The acute intervention will consist of 1 session of training following the program: Resistance Training Exercises. Each participant in the intervention group will perform resistance-training exercises in the form of a circuit. The circuit will consist of 10 repetitions per exercise of 7 exercises: leg press, bent-over row, bench press, squats, dumbbell jump squats with raises, dead-lifts and weighted abdominal crunches, with approximately 30 sec of rest in between each exercise (based on the estimated time needed to move from one position to the next). Initial intensity 6-7 of RPE and ending the set at 9-10. Each participant will move through the circuit 3 times, with 2 to 3 minutes of rest between each round.

Other: exercise training

Control

NO INTERVENTION

No intervention

Interventions

exercise training OTHER

high-intensity resistance training

Intervention

Eligibility Criteria

• Age: 18 Years - 30 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Participants between 18 and 30 years old
• Males and Females
• Healthy

You may not qualify if:

• Participants with known health problems such as cardiovascular, pulmonary or metabolic disease will be excluded.
• Pregnant females will be excluded from the study.
• Any adults found taking medications that affect endocrine or cardiovascular function will also be excluded from the study.
• Individuals found to be less than 110 pounds will also be excluded due to the collection of blood during this study.
• Participants that exercise more than three times per week or strength train more than twice per week will be excluded.
• Individuals that have poor venous access or have expressed a fear of needles or having blood taken will also be excluded.
• Cigarette smoking (current or those who quit within the previous 6 months
• Hypertension
• Overweight and obese
• Pre-diabetics

Sponsors & Collaborators

• Texas Tech University: lead

Study Sites (1)

Exercise and Sport Sciences Building

Lubbock, Texas, 79423, United States

Location

MeSH Terms

Interventions

Exercise

Intervention Hierarchy (Ancestors)

Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Officials

• Maria Fernandez del Valle, PhD

  Texas Tech University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: BASIC SCIENCE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: February 3, 2015
• First Posted: June 23, 2015
• Study Start: February 1, 2015
• Primary Completion: October 1, 2015
• Study Completion: December 1, 2015
• Last Updated: July 25, 2019

Record last verified: 2019-07

Locations

US (1)