Circulatory Levels of Irisin in Response to Chronic Resistance Training

NCT02475473 | Completed DMC

• 1 other identifier: 504792B
• Study Type: interventional
• Target: 28
• Locations: 1 country
• Sites: 1

Brief Summary

Study the responses of circulatory irisin to chronic high-intensity resistance training

Conditions

Healthy

Keywords

Volunteers

Outcome Measures

Primary Outcomes (8)

• Change in Serum irisin levels

  Baseline and 3 weeks

• Blood Lactate levels

  Intensity of exercise on sessions 1, 3, 6 and 9

  3 weeks

• Changes in physical fitness levels as meassured by 1RM (repetition maximum) and Cardio-respiratory maximal testing

  Baseline and 3 weeks

• Changes in Body composition assessment: DEXA and anthropometry

  Baseline and 3 weeks

• Changes in Blood glucose levels

  Baseline and 3 weeks

• Changes in Hematocrit concentration

  Baseline and 3 weeks

• Diet assessment: 24 hour recall and Food Preference Questionnaire

  3 weeks

• Physical Activity assessment: accelerometry

  3 weeks

Study Arms (2)

Intervention

EXPERIMENTAL

The acute intervention will consist of 1 session of training following the program: Resistance Training Exercises. Each participant in the intervention group will perform resistance-training exercises in the form of a circuit. The circuit will consist of 10 repetitions per exercise of 7 exercises: leg press, bent-over row, bench press, squats, dumbbell jump squats with raises, dead-lifts and weighted abdominal crunches, with approximately 30 sec of rest in between each exercise (based on the estimated time needed to move from one position to the next). Initial intensity 6-7 of RPE and ending the set at 9-10. Each participant will move through the circuit 3 times, with 2 to 3 minutes of rest between each round.

Other: Exercise Training

Control

NO INTERVENTION

Control

Interventions

Exercise Training OTHER

Chronic High-Intensity Resistance Training

Intervention

Eligibility Criteria

• Age: 18 Years - 30 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may not qualify if:

• Known health problems such as cardiovascular, pulmonary or metabolic disease will be excluded.
• Pregnant females.
• Any adults found taking medications that affect endocrine or cardiovascular function will also be excluded from the study.
• Individuals found to be less than 110 pounds.
• Participants that exercise more than three times per week or strength train more than twice per week.
• Individuals that have poor venous access or have expressed a fear of needles or having blood taken will also be excluded.
• Cigarette smoking (current or those who quit within the previous 6 months
• Hypertension
• Overweight and obese
• Pre-diabetics

Sponsors & Collaborators

• Texas Tech University: lead

Study Sites (1)

Exercise and Sport Sciences Building

Lubbock, Texas, 79423, United States

Location

MeSH Terms

Interventions

Exercise

Intervention Hierarchy (Ancestors)

Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Officials

• Maria Fernandez del Valle, PhD

  Texas Tech University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: BASIC SCIENCE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: February 3, 2015
• First Posted: June 18, 2015
• Study Start: February 1, 2015
• Primary Completion: October 1, 2015
• Last Updated: October 20, 2015

Record last verified: 2015-09

Locations

US (1)