High-Sensitivity Troponin T Plasma Levels in Patients With Aortic Stenosis (Tyrolean Aortic Stenosis Study-2)
TASS-2
1 other identifier
observational
10,000
1 country
1
Brief Summary
TASS-2 (Tyrolean Aortic Stenosis Study-2) aims to characterize the clinical value of minimally elevated troponin T plasma levels both in patients with asymptomatic and symtomatic aortic stenosis.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Jun 2015
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
May 15, 2015
CompletedFirst Posted
Study publicly available on registry
May 19, 2015
CompletedStudy Start
First participant enrolled
June 1, 2015
CompletedPrimary Completion
Last participant's last visit for primary outcome
October 1, 2025
CompletedStudy Completion
Last participant's last visit for all outcomes
October 1, 2025
CompletedAugust 1, 2024
July 1, 2024
10.3 years
May 15, 2015
July 31, 2024
Conditions
Outcome Measures
Primary Outcomes (1)
Mortality (overall, cardiovascular)
up to 8 years
Study Arms (2)
Aortic Valve Intervention
Consecutive symptomatic patients who underwent aortic valve intervention (SAVR or TAVI) for the treatment of severe AS since 2010
Conservative Treatment
Asymptomatic patients with aortic stenosis followed conservatively at our department
Interventions
Surgical or interventional aortic valve implantation
Eligibility Criteria
One patient cohort consists of patients with severe symptomatic aortic stenosis admitted for planned valve operation since 2010, when involved institutions started to routinely analyse hsTnT plasma levels. The other patient cohort consists of asymptomatic patients with aortic stenosis diagnosed treated conservatively.
You may qualify if:
- aortic stenosis detected by echocardiography / invasively
You may not qualify if:
- acute coronary syndrome
- endocarditis
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Medical University Innsbruck
Innsbruck, Tyrol, 6020, Austria
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Wolfgang Dichtl, MD, PhD
Medical University Innsbruck
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- RETROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Priv.-Doz. DDr.
Study Record Dates
First Submitted
May 15, 2015
First Posted
May 19, 2015
Study Start
June 1, 2015
Primary Completion
October 1, 2025
Study Completion
October 1, 2025
Last Updated
August 1, 2024
Record last verified: 2024-07