Key Insights

Highlights

Success Rate

88% trial completion (above average)

Published Results

38 trials with published results (12%)

Research Maturity

130 completed trials (42% of total)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 50/100

Termination Rate

5.5%

17 terminated out of 308 trials

Success Rate

88.4%

+1.9% vs benchmark

Late-Stage Pipeline

9%

28 trials in Phase 3/4

Results Transparency

29%

38 of 130 completed with results

Key Signals

38 with results88% success17 terminated

Data Visualizations

Phase Distribution

164Total
Not Applicable (126)
Early P 1 (3)
P 1 (1)
P 2 (6)
P 3 (8)
P 4 (20)

Trial Status

Completed130
Recruiting57
Unknown45
Not Yet Recruiting23
Terminated17
Active Not Recruiting15

Trial Success Rate

88.4%

Benchmark: 86.5%

Based on 130 completed trials

Clinical Trials (308)

Showing 20 of 20 trials
NCT07197736Recruiting

DELINEATE-Prospective

NCT05171712Not ApplicableCompleted

Portico and Navitor India Clinical Trial

NCT05646381Phase 2RecruitingPrimary

A Multicenter Trial Assessing the Impact of Lipoprotein(a) Lowering With Pelacarsen (TQJ230) on the Progression of Calcific Aortic Valve Stenosis

NCT07450196Not Yet RecruitingPrimary

A Prospective, Multicenter, Observational Study Evaluating Safety and Effectiveness of SAPIEN 3 Transcatheter Aortic Valve Replacement for Type-0 Bicuspid Aortic Valve Stenosis Patients in China

NCT07278310Not ApplicableRecruiting

STAR Trial (Siegel Transcatheter Aortic Valve Replacement in Patients With Symptomatic Severe Aortic Stenosis)

NCT05712161Not ApplicableActive Not RecruitingPrimary

Use of DurAVR™ THV System in Subjects With Severe Aortic Stenosis: Early Feasibility Study

NCT03383445Not ApplicableActive Not Recruiting

Transcatheter Aortic Valve Replacement Versu Surgical Aortix Valve Replacement for Treating Elderly Patients With Severe Aortic Stenosis and Small Aortic Annuli: A Prospective Randomized Study The VIVA Trial

NCT07479992Not Yet RecruitingPrimary

Multicenter Study for the Validation of Willem AI: Aortic StenoSis Early Diagnosis With AI-electrocardiogram Study

NCT07317804Phase 4Not Yet RecruitingPrimary

Echo-Guided vs Fluoroscopy-Guided Transcatheter Aortic Valve Replacement in Patients With Aortic Stenosis(ECHO-TAVR)

NCT06580158RecruitingPrimary

AI in Outpatient Practice for Diagnosing Aortic Stenosis and Diastolic Dysfunction

NCT07035847Not ApplicableRecruitingPrimary

Transaxillary TAVR With Solely Echocardiography Guidance

NCT07430267Not ApplicableNot Yet RecruitingPrimary

Dilation Optimisation for Uniform Bioprosthetic Leaflet Expansion

NCT07420907Recruiting

Study of the Progression of Chronic Cardiovascular Conditions

NCT06777368RecruitingPrimary

REdo tranScatheter Aortic Valve Replacement for Transcatheter aOrtic Valve failuRE

NCT06749132Not Yet RecruitingPrimary

Deep Learning-enhanced Personalized Monitoring of Aortic Stenosis - The DETECT-AS Prognostic Study

NCT07276711Not ApplicableNot Yet Recruiting

CAPTURE-2: Controlled Arterial Protection to Ultimately Remove Embolic Material

NCT05614986Completed

Prospective Evaluation of Neurocognition in Patients Undergoing Transcatheter Aortic Valve Replacement

NCT07170306Not Yet RecruitingPrimary

Cardiac Amyloidosis in Patients With Aortic Stenosis

NCT02675114Not ApplicableActive Not RecruitingPrimary

PARTNER 3 Trial: Safety and Effectiveness of the SAPIEN 3 Transcatheter Heart Valve in Low Risk Patients With Aortic Stenosis

NCT04126018Recruiting

Comparative Imaging Assessment of Valvular Heart Disease

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