Key Insights

Highlights

Success Rate

89% trial completion (above average)

Published Results

38 trials with published results (12%)

Research Maturity

137 completed trials (42% of total)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 50/100

Termination Rate

5.3%

17 terminated out of 323 trials

Success Rate

89.0%

+2.4% vs benchmark

Late-Stage Pipeline

9%

28 trials in Phase 3/4

Results Transparency

28%

38 of 137 completed with results

Key Signals

38 with results89% success17 terminated

Data Visualizations

Phase Distribution

171Total
Not Applicable (132)
Early P 1 (3)
P 1 (1)
P 2 (7)
P 3 (8)
P 4 (20)

Trial Status

Completed137
Recruiting59
Unknown44
Not Yet Recruiting27
Terminated17
Active Not Recruiting16

Trial Success Rate

89.0%

Benchmark: 86.6%

Based on 137 completed trials

Clinical Trials (323)

Showing 20 of 20 trials
NCT06171737Not ApplicableEnrolling By InvitationPrimary

Promoting Shared Decision Making for Severe Aortic Stenosis

NCT06777368RecruitingPrimary

REdo tranScatheter Aortic Valve Replacement for Transcatheter aOrtic Valve failuRE

NCT06047561RecruitingPrimary

The Scottish Aortic Stenosis LongiTudinal Imaging and biomarkeR (SALTIRE) Programme

NCT07827105Enrolling By InvitationPrimary

ECG-based AI Screening for Cases of Undiagnosed Moderate-to-Severe Aortic Stenosis in the Primary Care Setting

NCT03735667Not ApplicableActive Not RecruitingPrimary

ACURATE IDE: Safety and Effectiveness Study of ACURATE Valve for Transcatheter Aortic Valve Replacement

NCT07539259Phase 2Not Yet RecruitingPrimary

Regression in Left Ventricular Hypertrophy and Fibrosis in Aortic Stenosis

NCT07806409Not ApplicableNot Yet Recruiting

Safety and Clinical Performance of the Next-Generation SAFESYNC Transcatheter Heart Valve in Patients With Severe Aortic Stenosis

NCT06924151Not ApplicableRecruitingPrimary

Isolated Surgical Aortic Valve Replacement in Low Risk AS Patients

NCT07798713Active Not RecruitingPrimary

Quality of Life After Transcatheter Aortic Valve Implantation

NCT07794436RecruitingPrimary

Association Between Changes in Aortic Valve Area and Pulmonary Congestion After Transcatheter Aortic Valve Implantation

NCT07276711Not ApplicableRecruiting

CAPTURE-2: Controlled Arterial Protection to Ultimately Remove Embolic Material

NCT06470022Not ApplicableActive Not RecruitingPrimary

Comparison of Evolut FX Versus Sapien 3 Ultra Resilia.

NCT07604402Not ApplicableRecruitingPrimary

TRanscatheter Aortic-Valve Implantation Without On-site Cardiac Surgery

NCT07205068Not ApplicableRecruitingPrimary

Improved Outcomes With Pre-Procedure Shockwave IVL of Common Femoral Artery Access Site Prior to Large Bore Access and Pre-Closure

NCT07756398Not ApplicableNot Yet Recruiting

Importance of Point-of-Care Ultrasound for Early Detection of Valvular and Cardiac Diseases (IMPROVE)

NCT07420907Recruiting

Study of the Progression of Chronic Cardiovascular Conditions

NCT05756608CompletedPrimary

Fibrosis in Chronic and Delayed Myocardial Infarction

NCT07738575Not ApplicableNot Yet Recruiting

Same-Day Versus Standard Hospital Discharge After TAVI (HOME-TAVI)

NCT07739316Not ApplicableNot Yet RecruitingPrimary

Systematic Ambulatory ECG Monitoring Following TAVI

NCT06894550Not ApplicableCompletedPrimary

Short-term Exposure to High Altitude in Patients With Asymptomatic Aortic Stenosis

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