NCT02429739

Brief Summary

The main aim of this interventional study is to investigate whether the effects of computerized working memory training improves reading abilities for children, i.e. ages 9 - 16 years, diagnosed with dyslexia.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
32

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Oct 2014

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2014

Completed
7 months until next milestone

First Submitted

Initial submission to the registry

April 24, 2015

Completed
5 days until next milestone

First Posted

Study publicly available on registry

April 29, 2015

Completed
11 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2016

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2016

Completed
Last Updated

April 26, 2016

Status Verified

April 1, 2016

Enrollment Period

1.5 years

First QC Date

April 24, 2015

Last Update Submit

April 25, 2016

Conditions

Keywords

Working Memory Training, computerizedDyslexiaReading fluencyReading comprehension

Outcome Measures

Primary Outcomes (1)

  • Reading fluency, comprehension and speed

    LOGOS (http://www.logos-test.no) is a standardized Norwegian computerized test for reading processes. 6 subtest; reading fluency, reading comprehension, word recognition, phonological reading, orthographic reading, rapid naming of common objects

    Change from Baseline assessment to follow-up testing in 14 weeks

Secondary Outcomes (1)

  • Working Memory Capacity

    Change from Baseline assessment to follow-up testing in 14 week

Other Outcomes (1)

  • Executive function

    Before and after training period of 5 weeks

Study Arms (2)

Working Memory Training

EXPERIMENTAL

Behavioral: Cogmed RM working memory training. After baseline assessment participants will be randomized to active training or treatment as usual (waiting). The active group will start immediately and will have 6 weeks to perform the 25 training sessions.

Behavioral: Working memory Training

Passive control group

NO INTERVENTION

The control group will receive "treatment as usual" (Ordinary school days, special education if normally received).

Interventions

The child will use the computer program at home under parental supervision for 25 sessions, each lasting 30 - 45 minutes and the family has 6 weeks to complete the training. Each session consist 8 different tasks presented by an animated robot. The tasks all require the child to hold information in working memory and to manipulate the information. Other name: Cogmed RoboMemo

Working Memory Training

Eligibility Criteria

Age9 Years - 16 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)

You may qualify if:

  • Dyslexia

You may not qualify if:

  • Mental retardation (IQ below 70)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Sorlandet Hospital

Arendal, Aust-Agder, 4801, Norway

Location

Related Publications (12)

  • Baddeley A. The episodic buffer: a new component of working memory? Trends Cogn Sci. 2000 Nov 1;4(11):417-423. doi: 10.1016/s1364-6613(00)01538-2.

    PMID: 11058819BACKGROUND
  • Baddeley A. Working memory and language: an overview. J Commun Disord. 2003 May-Jun;36(3):189-208. doi: 10.1016/s0021-9924(03)00019-4.

    PMID: 12742667BACKGROUND
  • Klingberg T. Training and plasticity of working memory. Trends Cogn Sci. 2010 Jul;14(7):317-24. doi: 10.1016/j.tics.2010.05.002. Epub 2010 Jun 16.

    PMID: 20630350BACKGROUND
  • Klingberg, T (2012). Slik lærer hjernen. Oslo: Pax forlag

    BACKGROUND
  • Gathercole SE, Alloway TP. Practitioner review: short-term and working memory impairments in neurodevelopmental disorders: diagnosis and remedial support. J Child Psychol Psychiatry. 2006 Jan;47(1):4-15. doi: 10.1111/j.1469-7610.2005.01446.x.

  • Beneventi H, Tonnessen FE, Ersland L, Hugdahl K. Executive working memory processes in dyslexia: behavioral and fMRI evidence. Scand J Psychol. 2010 Jun 1;51(3):192-202. doi: 10.1111/j.1467-9450.2010.00808.x. Epub 2010 Mar 15.

  • Holmes J, Gathercole SE, Dunning DL. Adaptive training leads to sustained enhancement of poor working memory in children. Dev Sci. 2009 Jul;12(4):F9-15. doi: 10.1111/j.1467-7687.2009.00848.x.

  • Cogmed Working Memory Training (2012) Pearson assesment.no

    RESULT
  • Hulme, C & Snowling, M.J.(2009) Developmental Disorders and Language Learning and Cognition, Chichester, WS.: Wiley - Blackwell

    RESULT
  • Høien, T (2012) LOGOS; Teoribasert diagnostisering av lesevansker, Logometrica

    RESULT
  • Ottem, E og Frost, J (2010) Språk 6-16 Screeningtest, Statped, Bredtvet kompetansesenter

    RESULT
  • Swanson, H.L. (2006). Working memory and reading disabilities. I Alloway, T. & Gathercole, S (Red), Working Memory and Neurodevelopmental Disorders. (s. 59 - 88 9, Hove (UK): Psychology Press

    RESULT

Related Links

MeSH Terms

Conditions

Dyslexia

Condition Hierarchy (Ancestors)

Language DisordersCommunication DisordersNeurobehavioral ManifestationsNeurologic ManifestationsNervous System DiseasesSpecific Learning DisorderLearning DisabilitiesSigns and SymptomsPathological Conditions, Signs and SymptomsNeurodevelopmental DisordersMental Disorders

Study Officials

  • Gro CC Lohaugen, Phd

    Sorlandet Hospital HF

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER GOV
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 24, 2015

First Posted

April 29, 2015

Study Start

October 1, 2014

Primary Completion

April 1, 2016

Study Completion

April 1, 2016

Last Updated

April 26, 2016

Record last verified: 2016-04

Locations