NCT03364010

Brief Summary

The investigators hypothesize that children with dyslexia present proprioceptive disorders and the purpose of the present study is to better understand relationships between motor control, proprioception and academic learnings. The investigators compare a group of French students with and without dyslexia aged 10-12.

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
56

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jan 2018

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
terminated

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

September 27, 2017

Completed
2 months until next milestone

First Posted

Study publicly available on registry

December 6, 2017

Completed
29 days until next milestone

Study Start

First participant enrolled

January 4, 2018

Completed
1.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 9, 2019

Completed
2.1 years until next milestone

Study Completion

Last participant's last visit for all outcomes

June 2, 2021

Completed
Last Updated

May 14, 2026

Status Verified

February 1, 2023

Enrollment Period

1.3 years

First QC Date

September 27, 2017

Last Update Submit

May 11, 2026

Conditions

Dyslexia

Keywords

Motor controlProprioception

Outcome Measures

Primary Outcomes (1)

  • Evaluation of proprioception through velocity perception

    The ability to perceive motion at 3 different velocities for 3 different joints is assessed using a motorized ergometer. A passive movement is performed by the ergometer and children are tasked to press a button as soon as they feel the movement. We calculate the angle of detection for each speed and compare it between Dyslexic and healthy children.

    1day

Secondary Outcomes (5)

  • Evaluation of proprioception through position perception

    1 day

  • Motor learning

    1 day

  • Text reading

    1day

  • Phonological awareness: phonemic blending and phonemic elision

    1day

  • Identifying words

    1day

Study Arms (1)

Dyslexic and non dyslexic Children

EXPERIMENTAL

Children aged 10-12 Evaluation of proprioception Evaluation of motor learning Evaluation of written language

Behavioral: Evaluation of proprioceptionBehavioral: Evaluation of motor learningBehavioral: Evaluation of written language

Interventions

Evaluation of proprioceptionBEHAVIORAL

Velocity perception and Position perception

Dyslexic and non dyslexic Children
Evaluation of motor learningBEHAVIORAL

Motor accurancy and State Estimation with visual perturbations

Dyslexic and non dyslexic Children
Evaluation of written languageBEHAVIORAL

Text reading, Identifying words and Phonological awareness: phonemic blending and phonemic elision

Dyslexic and non dyslexic Children

Eligibility Criteria

Age10 Years - 12 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17)

You may qualify if:

  • Child with a French social security
  • School child
  • Native French speaker
  • right-handed
  • Normal or corrected vision
  • Without neurological or psychiatric histories
  • Agree to participate in the study in agreement with parental rights representatives
  • For the dyslexic group :
  • pluridisciplinary diagnostic
  • never consulted for proprioception before
  • without any other leaning disorders like dysphasia
  • attention deficit hyperactivity disorder (ADHD) or developmental coordination disorder (DCD)
  • For the control group :
  • regular school attendance
  • never consulted for learning disabilities
  • +1 more criteria

You may not qualify if:

  • genetic disorder
  • neurological or psychiatric history
  • Delayed psychomotor development
  • Reeducation or current treatment interfering with the evaluation

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Inserm U1093

Dijon, Bourgogne-Franche-Comté, 21000, France

Location

Related Publications (1)

  • Laprevotte J, Papaxanthis C, Saltarelli S, Quercia P, Gaveau J. Movement detection thresholds reveal proprioceptive impairments in developmental dyslexia. Sci Rep. 2021 Jan 11;11(1):299. doi: 10.1038/s41598-020-79612-4.

    PMID: 33431949RESULT

MeSH Terms

Conditions

Dyslexia

Condition Hierarchy (Ancestors)

Language DisordersCommunication DisordersNeurobehavioral ManifestationsNeurologic ManifestationsNervous System DiseasesSpecific Learning DisorderLearning DisabilitiesSigns and SymptomsPathological Conditions, Signs and SymptomsNeurodevelopmental DisordersMental Disorders

Study Officials

  • Patrick QUERCIA, dr

    Unité Inserm d'affiliation : Laboratoire U1093 Cognition, Action et Plasticité Sensorimotrice

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
BASIC SCIENCE
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER GOV
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 27, 2017

First Posted

December 6, 2017

Study Start

January 4, 2018

Primary Completion

May 9, 2019

Study Completion

June 2, 2021

Last Updated

May 14, 2026

Record last verified: 2023-02

Locations

FR(1)