Assessment of Visual Dyslexia Remediation Protocols - Dyslexia REMEDIATION

NCT05514457 | Completed

• 1 other identifier: 69HCL21_0736
• Study Type: interventional
• Target: 13
• Locations: 1 country
• Sites: 1

Brief Summary

Dyslexia is first described as a phonological deficit. Several studies report a neurovisual deficit in dyslexics. Some dyslexics have a visual deficit without phonological impairment, others have a pure phonological deficit, and still others have both types of deficits. From this observation the idea emerged to propose specific remediation protocols for people with visual impairments and to assess their effects on reading. At the theoretical level, if visual stimulation is able to improve reading performance, it is the demonstration of the existence of visual origin of dyslexia. At the clinical level, such a result not only opens the prospect of a different and more adapted rehabilitation for these types of dyslexia, but also the prospect, if the visual deficits are pre-existing to the learning of reading, to use them for early diagnosis and management.

Conditions

Dyslexia

Keywords

Dyslexia; Remediation; Visual attention span; Visual search

Outcome Measures

Primary Outcomes (2)

• reading performance

  change in reading time

  for arm 1: at baseline at 1 month at 2 month at 3 month For arm 2: 4 times in the same day, 4 consecutive reading sessions with a break in-between of minimum 5 minutes

• reading performance

  change in number of errors

  for arm 1: at baseline at 1 month at 2 month at 3 month For arm 2: 4 times in the same day, 4 consecutive reading sessions with a break in-between of minimum 5 minutes

Secondary Outcomes (4)

• score of Elementary Visuo-Spatial Perception test

  one time at baseline

• visual attention span

  one time at baseline

• Visual search time

  one time at baseline

• performance score on the phonology tests (EVALéo 6-15 = Evaluation of written language and oral language 6-15 years)

  one time at baseline

Study Arms (2)

remediation group 1

EXPERIMENTAL

dyslexic children

Behavioral: visual stimulation with I pad

remediation group 2

EXPERIMENTAL

dyslexic children

Behavioral: visual stimulation with lamp

Interventions

visual stimulation with I pad BEHAVIORAL

At the beginning of the study, for baseline condition, children will do 4 tests (visuo-spatial perception test, visual attention span, visual research, phonology tests). In the first group of the study, the children will do visual research exercises on I pad 10 minutes per day during one month = remediation. They will also do 4 reading aloud tests, once a month, for 3 months. The remediation exercises will be realized during the first, second or third month.

remediation group 1

visual stimulation with lamp BEHAVIORAL

At the beginning of the study, for baseline condition, children will do the 4 tests like group 1. In the second group of the study, the children will do reading aloud tests, with lamp adjusted with different parameters = remediation (passive visual stimulation of a specific frequency believed to promote visual processing of written symbols).

remediation group 2

Eligibility Criteria

• Age: 8 Years - 12 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17)

You may qualify if:

• Male or female
• Aged 8 to 12
• Diagnosed dyslexics
• Normal or corrected to normal vision
• Legal guardians of children subjects providing their free, informed and written consent to participate in the study; With the child also giving orally his consent to participate.

You may not qualify if:

• other neurodevelopmental problem
• strabismus, amblyopia
• For the glasses (group 2) : epileptic child are excluded

Sponsors & Collaborators

• Hospices Civils de Lyon: lead

Study Sites (1)

Centre de Recherche en Neurosciences de Lyon

Bron, Auvergne-Rhône-Alpes, 69500, France

Location

MeSH Terms

Conditions

Dyslexia

Interventions

Photic Stimulation; Protein-Arginine Deiminases; Light

Condition Hierarchy (Ancestors)

Language Disorders; Communication Disorders; Neurobehavioral Manifestations; Neurologic Manifestations; Nervous System Diseases; Specific Learning Disorder; Learning Disabilities; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Neurodevelopmental Disorders; Mental Disorders

Intervention Hierarchy (Ancestors)

Physical Stimulation; Investigative Techniques; Hydrolases; Enzymes; Enzymes and Coenzymes; Electromagnetic Radiation; Electromagnetic Phenomena; Magnetic Phenomena; Physical Phenomena; Optical Phenomena; Radiation; Radiation, Nonionizing

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: BASIC SCIENCE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: August 5, 2022
• First Posted: August 24, 2022
• Study Start: November 17, 2022
• Primary Completion: March 15, 2024
• Study Completion: March 15, 2024
• Last Updated: September 25, 2024

Record last verified: 2024-09

Data Sharing

• IPD Sharing: Will not share

Locations

FR (1)