NCT02384564

Brief Summary

The purpose of this study is to determine whether there is a clinically relevant difference in first attempt success rates between the Ambu King Vision Video Laryngoscope and Direct Laryngoscopy in Children.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
140

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Aug 2015

Shorter than P25 for not_applicable

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

February 26, 2015

Completed
12 days until next milestone

First Posted

Study publicly available on registry

March 10, 2015

Completed
5 months until next milestone

Study Start

First participant enrolled

August 1, 2015

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2015

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2015

Completed
Last Updated

July 29, 2015

Status Verified

July 1, 2015

Enrollment Period

2 months

First QC Date

February 26, 2015

Last Update Submit

July 27, 2015

Conditions

Keywords

LaryngoscopyVideo LaryngoscopyTracheal intubation

Outcome Measures

Primary Outcomes (1)

  • First Attempt Success Rate of Tracheal Intubation

    An attempt at tracheal intubation will be defined as entry of the device into the patient's mouth without the need to remove the device once entered and securing the airway.

    Assessed intraoperatively at time of intubation

Secondary Outcomes (5)

  • Grades of Laryngeal View

    Assessed intraoperatively at time of intubation

  • Time to Successful Intubation

    Assessed intraoperatively at time of intubation

  • Intraoperative Complications

    Assessed intraoperatively for the duration of the surgery

  • Postoperative Complications

    Outcome measure will be assessed postoperatively in the immediate phase 1 recovery unit for an average of 1 hour.

  • Ease of Endotracheal Tube Passage

    Assessed intraoperatively at time of intubation

Study Arms (2)

Ambu King Vision Video Laryngoscope aBlade System

EXPERIMENTAL

The trachea will be intubated using the Ambu King Vision Video Laryngoscope with the appropriate sized blade (size 1 or 2) based on manufacturer guidelines and clinical judgement.

Device: Ambu King Vision Video Laryngoscope aBlade

Direct Laryngoscope

ACTIVE COMPARATOR

The trachea will be intubated via direct laryngoscopy using a traditional straight blade laryngoscope, with appropriately sized blade based on manufacturer guidelines and clinical judgement.

Device: Direct Laryngoscopy via Miller Straight Blade

Interventions

At time of tracheal intubation, the subject will be intubated using the Ambu King Vision Video Laryngoscope with the appropriately sized Ambu aBlade System based on manufacturer guidelines and clinical judgement. The first attempt to successful intubation will be assessed. The Cormack Lehane and Percentage of Glottic Opening scores will be recorded via direct vision. Information on subsequent attempts, time to successful intubation, and ease of tracheal tube insertion will be assessed.

Also known as: King Vision Video Laryngoscope
Ambu King Vision Video Laryngoscope aBlade System

At time of tracheal intubation, the subject will be intubated via direct laryngoscopy using a straight laryngoscope blade, based on manufacturer guidelines and clinical judgement. The first attempt to successful intubation will be assessed. The Cormack Lehane and Percentage of Glottic Opening scores will be recorded via direct vision. Information on subsequent attempts, time to successful intubation, and ease of tracheal tube insertion will be assessed.

Also known as: Miller Blade, Wisconsin blade, Straight blade
Direct Laryngoscope

Eligibility Criteria

Age1 Day - 11 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)

You may qualify if:

  • ASA (American Society of Anesthesiologists) I-III classified patients
  • Patients undergoing procedure where an endotracheal tube would be normally utilized

You may not qualify if:

  • Children with expected difficult airways
  • Coagulopathy

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (4)

  • Levitan RM, Heitz JW, Sweeney M, Cooper RM. The complexities of tracheal intubation with direct laryngoscopy and alternative intubation devices. Ann Emerg Med. 2011 Mar;57(3):240-7. doi: 10.1016/j.annemergmed.2010.05.035. Epub 2010 Jul 31.

    PMID: 20674088BACKGROUND
  • Theiler L, Hermann K, Schoettker P, Savoldelli G, Urwyler N, Kleine-Brueggeney M, Arheart KL, Greif R. SWIVIT--Swiss video-intubation trial evaluating video-laryngoscopes in a simulated difficult airway scenario: study protocol for a multicenter prospective randomized controlled trial in Switzerland. Trials. 2013 Apr 4;14:94. doi: 10.1186/1745-6215-14-94.

    PMID: 23556410BACKGROUND
  • Murphy LD, Kovacs GJ, Reardon PM, Law JA. Comparison of the king vision video laryngoscope with the macintosh laryngoscope. J Emerg Med. 2014 Aug;47(2):239-46. doi: 10.1016/j.jemermed.2014.02.008. Epub 2014 Apr 16.

    PMID: 24742495BACKGROUND
  • Akihisa Y, Maruyama K, Koyama Y, Yamada R, Ogura A, Andoh T. Comparison of intubation performance between the King Vision and Macintosh laryngoscopes in novice personnel: a randomized, crossover manikin study. J Anesth. 2014 Feb;28(1):51-7. doi: 10.1007/s00540-013-1666-9. Epub 2013 Jun 30.

    PMID: 23812581BACKGROUND

Study Officials

  • narasimhan jagannathan, MD

    Ann & Robert Lurie Children's Hospital of Chicago

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Narasimhan Jagannathan, MD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Primary Investigator; M.D.

Study Record Dates

First Submitted

February 26, 2015

First Posted

March 10, 2015

Study Start

August 1, 2015

Primary Completion

October 1, 2015

Study Completion

October 1, 2015

Last Updated

July 29, 2015

Record last verified: 2015-07