NCT02356718

Brief Summary

This study examines whether computer tasks can improve memory and other cognitive functions among patients receiving inpatient treatment for substance use disorders.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
111

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Jan 2015

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2015

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

February 2, 2015

Completed
3 days until next milestone

First Posted

Study publicly available on registry

February 5, 2015

Completed
1.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2016

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2016

Completed
Last Updated

July 27, 2016

Status Verified

July 1, 2016

Enrollment Period

1.5 years

First QC Date

February 2, 2015

Last Update Submit

July 25, 2016

Conditions

Outcome Measures

Primary Outcomes (1)

  • Auditory memory capacity - WAIS Digit Span score

    WAIS Digit Span score

    Baseline, 3 weeks

Secondary Outcomes (4)

  • Auditory memory capacity - WAIS Letter-number sequencing score

    Baseline to 3 weeks

  • Visual memory capacity - WMS Spatial span score

    Baseline to 3 weeks

  • Visual memory capacity - WMS Symbol span score

    Baseline to 3 weeks

  • Training progress score - Cognitive progress indicator score

    Baseline to 4 weeks

Study Arms (2)

Experimental

EXPERIMENTAL

Computerized cognitive training activities

Behavioral: Cognitive training activitiesBehavioral: Inpatient psychosocial therapy

Control

ACTIVE COMPARATOR

Non-adaptive computerized cognitive training activities

Behavioral: Cognitive training activitiesBehavioral: Inpatient psychosocial therapy

Interventions

Training activities consist of computer tasks designed to improve memory and cognition. The intervention consists of 45-minute training sessions delivered regularly during inpatient treatment.

ControlExperimental

Group psychosocial therapy delivered in an inpatient setting.

ControlExperimental

Eligibility Criteria

Age18 Years - 60 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Participants must be patients registered for inpatient treatment at the Centre for Addiction and Mental Health
  • Age 18-60
  • Fluency in English
  • Able to attend scheduled training sessions
  • Comfortable using a computer and mouse

You may not qualify if:

  • Severe cognitive impairment
  • Current or past psychosis or diagnosis of schizophrenia
  • Photosensitive epilepsy or history of seizures triggered by light
  • Legal mandate to attend treatment

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Centre for Addiction and Mental Health

Toronto, Ontario, Canada

Location

Related Publications (1)

  • Hendershot CS, Wardell JD, Vandervoort J, McPhee MD, Keough MT, Quilty LC. Randomized trial of working memory training as an adjunct to inpatient substance use disorder treatment. Psychol Addict Behav. 2018 Dec;32(8):861-872. doi: 10.1037/adb0000415. Epub 2018 Nov 26.

Related Links

MeSH Terms

Conditions

Substance-Related Disorders

Condition Hierarchy (Ancestors)

Chemically-Induced DisordersMental Disorders

Study Officials

  • Christian Hendershot, PhD

    Centre for Addiction and Mental Health

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Professor

Study Record Dates

First Submitted

February 2, 2015

First Posted

February 5, 2015

Study Start

January 1, 2015

Primary Completion

July 1, 2016

Study Completion

July 1, 2016

Last Updated

July 27, 2016

Record last verified: 2016-07

Locations