Effectiveness of a Brief Cognitive and Behavioral Skills Program on Stage Transitions for Chronic Ketamine Abusers

NCT03644719 | Completed

• 1 other identifier: Chronic Ketamine Abusers
• Study Type: interventional
• Target: 409
• Locations: 0 countries
• Sites: N/A

Brief Summary

In recent years ketamine abuse becomes prevalent in youth in some Asian countries. Chronic ketamine abuse may lead to uropathology and cognitive impairments. No pharmacological interventions have been identified as effective for treating ketamine abuse or helpful in achieving or maintaining abstinence from ketamine. Cognitive-behavioral treatment is currently an important psychosocial intervention for addictive problems. This study aimed to test whether a brief cognitive-behavioral training program has a positive influence on stage transitions among ketamine abusers.

Conditions

Substance Use Disorders

Keywords

Substance Abuse; Cognitive behavioral treatment; Ketamine; Stage of Change

Outcome Measures

Primary Outcomes (1)

• Motivation to change

  Stage of Change Scale: Have you thought of abstaining from Ketamine? In 30 days? In six months?

  15 minutes

Secondary Outcomes (1)

• Knowledge about ketamine

  3 minutes

Study Arms (2)

Cognitive behavior skills training

EXPERIMENTAL

The first session is intended to establish rapport, build therapeutic cohesion through ice-breaking activities, and educate participants about the drug regulations stated in the Statute for Drug Hazard Prevention and Control. The following four sessions are devoted to interactively practicing refusal skills, communication skills, decision-making skills, and positive conflict resolution skills. The final session is to review what has been learned and reminds participants about the association of drug use with HIV/HCV.

Behavioral: Cognitive behavioral skills training

Education as usual

NO INTERVENTION

The EAU group received six hours of informational lectures about ketamine, its effects on the brain, relevant regulations and laws, and the risks and modes of transmission of infectious diseases, including HIV and hepatitis C.

Interventions

Cognitive behavioral skills training BEHAVIORAL

A brief cognitive behavioral skills training was applied to teach ketamine abusers about stimulus control, refusal skills, communication skills, decisional balance, and infectious diseases prevention.

Cognitive behavior skills training

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• ketamine use in 30 days
• more than 18 years old

You may not qualify if:

• no brain damage

Sponsors & Collaborators

• National Taiwan University: lead

Related Publications (1)

• Baker A, Lee NK, Claire M, Lewin TJ, Grant T, Pohlman S, Saunders JB, Kay-Lambkin F, Constable P, Jenner L, Carr VJ. Brief cognitive behavioural interventions for regular amphetamine users: a step in the right direction. Addiction. 2005 Mar;100(3):367-78. doi: 10.1111/j.1360-0443.2005.01002.x.

  PMID: 15733250 RESULT

Related Links

• This study demonstrated that brief interventions consisting of cognitive behavior therapy increased the likelihood of abstinence from amphetamines among those receiving two or more treatment sessions.

MeSH Terms

Conditions

Substance-Related Disorders

Condition Hierarchy (Ancestors)

Chemically-Induced Disorders; Mental Disorders

Study Officials

• Tony Szu-Hsien Lee, Ph.D.

  Health Promotion and Health Education

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Masking Details: Participants signed up for a time slot for cognitive behavioral skills training (CBST) or a time slot for education as usual (EAU), without being informed which was which.
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Model Details: Two arms were used to examine the relative effect of the cognitive behavioral skills training (CBSR) and a time slot for education as usual (EAU). The CBST consists of six sessions. The first session is intended to establish rapport, build therapeutic cohesion through ice-breaking activities, and educate participants about the drug regulations stated in the Statute for Drug Hazard Prevention and Control. The following four sessions are devoted to interactively practicing refusal skills, communication skills, decision-making skills, and positive conflict resolution skills. The final session is to review what has been learned and reminds participants about the association of drug use with HIV/HCV.

Study Record Dates

• First Submitted: August 12, 2018
• First Posted: August 23, 2018
• Study Start: August 19, 2014
• Primary Completion: March 19, 2017
• Study Completion: March 19, 2017
• Last Updated: August 23, 2018

Record last verified: 2018-08

Data Sharing

• IPD Sharing: Will not share