Key Highlights

Risk & Performance

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 45/100

Failure Rate

7.0%

28 terminated/withdrawn out of 402 trials

Success Rate

89.9%

+3.4% vs industry average

Late-Stage Pipeline

37 trials in Phase 3/4

Results Transparency

11%

28 of 250 completed trials have results

Key Signals

74 recruiting28 with results18 terminated10 withdrawn

Enrollment Performance

Analytics

N/A

276(74.4%)

Phase 2

39(10.5%)

Phase 4

31(8.4%)

Phase 1

15(4.0%)

Phase 3

6(1.6%)

Early Phase 1

4(1.1%)

371Total

N/A(276)

Phase 2(39)

Phase 4(31)

Phase 1(15)

+2 more

Activity Timeline

Global Presence

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Clinical Trials (402)

Showing 20 of 402 trials

NCT05017311Phase 4Recruiting

Optimized Predictive Treatment In Medications for Unipolar Major Depression (OPTIMUM-D)

Role: collaborator

NCT07105449Not ApplicableRecruiting

THC Titration of High-Potency Cannabis Concentrates

Role: lead

NCT07228923Not ApplicableCompleted

Development and Evaluation of a Theory and Evidence-based Intervention to Reduce Hazardous Alcohol Consumption Among Treatment Seeking Smokers

Role: lead

NCT06512220Phase 2Recruiting

Imaging the Effects of Serotonin 2A Receptor Modulation on Synaptic Density in Treatment-resistant Depression (SYNVEST)

Role: lead

NCT05748990Not ApplicableRecruiting

Does Abnormal Insulin Action in the Brain Underlie Cognitive and Metabolic Dysfunction in Schizophrenia

Role: lead

NCT02808533Not ApplicableActive Not Recruiting

Topiramate and Schizophrenia: Effects on Weight and Psychopathology

Role: lead

NCT05333003Not ApplicableActive Not Recruiting

Semaglutide in Comorbid Schizophrenia Spectrum Disorder and Obesity

Role: lead

NCT03741478Phase 1Active Not Recruiting

Intranasal Insulin and Olanzapine Study in Healthy Volunteers

Role: lead

NCT03414151Active Not Recruiting

Gut Microbiome in AP Naive

Role: lead

NCT05944926Phase 3Active Not Recruiting

Improving Outcomes in Depression in Primary Care in a Low Resource Setting

Role: collaborator

NCT04602741Not ApplicableCompleted

Examining a Digital Health Approach for Advancing Schizophrenia Illness Self-management and Provider Engagement

Role: lead

NCT07146633Not ApplicableRecruiting

Efficacy of an EMDR App for PTSD and SUD

Role: lead

NCT06746155Recruiting

Predictors of Relapse in Major Depressive Disorder (PERFORM-D)

Role: collaborator

NCT06299319Phase 1Enrolling By Invitation

Feasibility, Clinical Effects, and Safety of Psilocybin-assisted Psychotherapy for Treatment-resistant OCD

Role: lead

NCT04858490Not ApplicableCompleted

Remote Treatment of Alcohol Withdrawal

Role: lead

NCT06672562Not ApplicableActive Not Recruiting

Narrative Enhancement and Cognitive Therapy for Self-Stigma in Youth

Role: lead

NCT03191058Not ApplicableCompleted

Confirmatory Efficacy and Safety Trial of Magnetic Seizure Therapy for Depression

Role: collaborator

NCT06843187Phase 2Recruiting

Lemborexant for the Treatment of Residual Insomnia in Major Depressive Disorder (MDD)

Role: collaborator

NCT05710237Phase 2Completed

Does Psilocybin Require Psychedelic Effects to Treat Depression?

Role: lead

NCT05223959Not ApplicableCompleted

Culturally Adapted Psychoeducation for Bipolar Disorder in a Low-resource Setting: A Randomized Controlled Trial

Role: collaborator