NCT02319876|Unknown
Expression of TIM-3 on Lymphocytes in Sepsis
Expression and the Clinical Significance of TIM-3 on Lymphocytes During Sepsis
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Expression and the Clinical Significance of TIM-3 on Lymphocytes During Sepsis
Sponsor study identifier
Secondary identifiers
OTHER_GRANT · National Natural Science Foundation of China
observational
80
1 country
1
Study Start
February 2014
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
December 2015
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
Study Completion
December 2015
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
The current project was designed to examine the express TIM-3 on lymphocytes and monocytes and its role in immunosuppression during sepsis.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
December 2015
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
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Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
February 2014
Date type not reportedThis date has not been verified as actual or estimated.
December 15, 2014
Actual (reported)December 18, 2014
Actual (reported)December 2015
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
December 2015
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
TIM-3 expression on CD4+, CD8+ T cells and CD14+ monocytes
TIM-3 level on T cells was compared between different populations.
within 24h after recruitment
28-day mortality
28 days after diagnosis of sepsis
Patients with severe sepsis
Patients after elective surgeries presented with SIRS but without sepsis
Volunteers
Patients admitted in ICU at Changhai Hospital
Anesthesiology and Intensive Care, Changhai Hospital
Shanghai, Shanghai Municipality, 200433, China
Peripheral blood sample was collected to examine TIM-3 on CD4+ and CD8+ lymphocytes, and CD14+ monocytes. Monocyte HLA-DR will also be determined.
Xiaoming Deng, M.D., Ph.D.
Changhai Hospital
First Submitted
December 15, 2014
First Posted
December 18, 2014
Study Start
February 2014
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
December 2015
Relationship of Cerebral Perfusion Pressure Variability to Sepsis-associated Encephalopathy
Contact the study team to confirm eligibility.
This estimate has passed. The registry has not confirmed an actual date for this milestone.
Study Completion
December 2015
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
Last Updated
July 29, 2015
Record last verified: 2015-06
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