Epidemiology of Sepsis in China
Chinese Epidemiological Study of Severe Sepsis.(CHESS Study)
1 other identifier
observational
2,000
1 country
1
Brief Summary
Sepsis is a common cause for morbidity and mortality in critically ill patients. In USA, the incidence of sepsis is about 3/1000 population. However, the incidence of sepsis varies among different clinic trails. In addition, clinician empirical select antibiotic according to the epidemiology of sepsis, however, the etiology of sepsis is various in different studies. In China, the MDRO is much higher than western country. There is no study about the epidemiology of sepsis in China. Therefore, it is necessary to conduct a study about it in China.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Nov 2015
Shorter than P25 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
April 11, 2015
CompletedFirst Posted
Study publicly available on registry
May 19, 2015
CompletedStudy Start
First participant enrolled
November 1, 2015
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 1, 2015
CompletedStudy Completion
Last participant's last visit for all outcomes
January 1, 2016
CompletedFebruary 17, 2016
October 1, 2015
1 month
April 11, 2015
February 14, 2016
Conditions
Outcome Measures
Primary Outcomes (2)
Incidence
Patients will be assessed up to 90 days
Mortality
Sepsis and severe sepsis patients will be assessed up to 90 days
Secondary Outcomes (1)
etiology
The pathogen of sepsis will be assessed up to 90 days
Interventions
Eligibility Criteria
Sepsis patient who admitted into ICU
You may qualify if:
- sepsis patients who admitted into ICU during research period (include patients with sepsis at ICU admission and patients who has new sepsis during ICU period)
You may not qualify if:
- The patients with second sepsis in ICU
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Jianfeng Xielead
Study Sites (1)
Zhongda hospital, Southeast University
Nanjing, Jiangsu, 210009, China
Related Publications (2)
Xie J, Wang H, Kang Y, Zhou L, Liu Z, Qin B, Ma X, Cao X, Chen D, Lu W, Yao C, Yu K, Yao X, Shang H, Qiu H, Yang Y; CHinese Epidemiological Study of Sepsis (CHESS) Study Investigators. The Epidemiology of Sepsis in Chinese ICUs: A National Cross-Sectional Survey. Crit Care Med. 2020 Mar;48(3):e209-e218. doi: 10.1097/CCM.0000000000004155.
PMID: 31804299DERIVEDYang Y, Xie JF, Yu KJ, Yao C, Li JG, Guan XD, Yan J, Ma XC, Kang Y, Yang CS, Yao XQ, Shang HC, Qiu HB; for CHESS Study Investigators. Epidemiological Study of Sepsis in China: Protocol of a Cross-sectional Survey. Chin Med J (Engl). 2016 Dec 20;129(24):2967-2973. doi: 10.4103/0366-6999.195474.
PMID: 27958229DERIVED
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- STUDY DIRECTOR
Yang Yi, Ph.D.
Zhongda Hospital
Study Design
- Study Type
- observational
- Observational Model
- CASE ONLY
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR INVESTIGATOR
- PI Title
- Attending
Study Record Dates
First Submitted
April 11, 2015
First Posted
May 19, 2015
Study Start
November 1, 2015
Primary Completion
December 1, 2015
Study Completion
January 1, 2016
Last Updated
February 17, 2016
Record last verified: 2015-10