Identification Sepsis Related Single Nucleotide Polymorphism (SNP) by Whole Exome Sequencing
1 other identifier
observational
1,000
1 country
1
Brief Summary
Sepsis is a common cause of death in intensive care unit, timely and accurate diagnosis and treatment directly affect the survival rate. Single nucleotide polymorphism (SNP) was promising genetic biomarker for sepsis patients. The present study was designed to screen several SNP by whole exome sequencing which evaluate the sepsis related snp site in order to be a new target for the treatment of sepsis.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Jan 2013
Typical duration for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 1, 2013
CompletedFirst Submitted
Initial submission to the registry
August 8, 2013
CompletedFirst Posted
Study publicly available on registry
August 9, 2013
CompletedPrimary Completion
Last participant's last visit for primary outcome
January 1, 2015
CompletedStudy Completion
Last participant's last visit for all outcomes
December 1, 2015
CompletedAugust 9, 2013
August 1, 2013
2 years
August 8, 2013
August 8, 2013
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
sepsis related SNP site
28 days after admitted to ICU
Study Arms (2)
normal control
Sepsis group
Eligibility Criteria
within 24 hours after admited in ICU
You may qualify if:
- Clinical diagnosis of sepsis
- Patients who agree with the study
You may not qualify if:
- Aged \<18 years;
- Into the group who died within 24 hours;
- Agranulocytosis (\<0.5 × 109 / L);
- Combined HIV infection.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Chinese PLA general hospital
Beijing, Beijing Municipality, 100086, China
Biospecimen
whole blood sample
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- STUDY DIRECTOR
Huijuan Wang, Dr
Chinese PLA General Hospital
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- CASE CONTROL
- Time Perspective
- PROSPECTIVE
- Target Duration
- 28 Days
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Dr
Study Record Dates
First Submitted
August 8, 2013
First Posted
August 9, 2013
Study Start
January 1, 2013
Primary Completion
January 1, 2015
Study Completion
December 1, 2015
Last Updated
August 9, 2013
Record last verified: 2013-08