NCT02299869

Brief Summary

Comparative Study to Evaluate the Cosmetic Appearance of Two Brands (Coopervision (CVI) vs. Competitor)of Color Soft Contact Lenses

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
41

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Oct 2014

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2014

Completed
Same day until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2014

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2014

Completed
19 days until next milestone

First Submitted

Initial submission to the registry

November 20, 2014

Completed
4 days until next milestone

First Posted

Study publicly available on registry

November 24, 2014

Completed
1.8 years until next milestone

Results Posted

Study results publicly available

August 24, 2016

Completed
Last Updated

March 10, 2017

Status Verified

January 1, 2017

Enrollment Period

Same day

First QC Date

November 20, 2014

Results QC Date

July 25, 2016

Last Update Submit

January 30, 2017

Conditions

Outcome Measures

Primary Outcomes (5)

  • Cosmetic Appearance Preference

    Participant's subjective preference for cosmetic appearance. 3 point Likert Scale. 1=prefer CVI-test lens 2=prefer Competitor-control lens, 3=no preference

    20 minutes

  • Comfort

    Participant's subjective rating for comfort. (Scale 0-10, 0=poor, 10=excellent).

    Baseline

  • Comfort

    Participant's subjective rating for comfort. (Scale 0-10, 0=poor, 10=excellent).

    20 minutes

  • Comfort Preference

    Participant's subjective preference for comfort on a 3 point Likert Scale. 1=prefer CVI-test lens, 2=prefer Competitor-control lens, 3=no preference

    Baseline

  • Comfort Preference

    Participant's subjective preference for comfort on a 3 point Likert Scale. 1=prefer CVI-test lens, 2=prefer Competitor-control lens, 3=no preference

    20 minutes

Study Arms (4)

Group 1 - Verde (Competitor-control) vs. Green (CVI-test)

OTHER

Each subject was randomized to wear the test and control lenses contralaterally.

Device: Verde (Competitor-control)Device: Green (CVI-test)

Group 2 - Cinza (Competitor-control) vs. Grey (CVI-test)

OTHER

Each subject was randomized to wear the test and control lenses contralaterally.

Device: Cinza (Competitor-control)Device: Grey (CVI-test)

Group 3 - Esmeralda (Competitor-control) vs. Jade (CVI-test)

OTHER

Each subject was randomized to wear the test and control lenses contralaterally.

Device: Esmeralda (Competitor-control)Device: Jade (CVI-test)

Group 4 - Azul (Competitor-control) vs. Blue (CVI-test)

OTHER

Each subject was randomized to wear the test and control lenses contralaterally.

Device: Azul (Competitor-control)Device: Blue (CVI-test)

Interventions

contact lens

Also known as: methafilcon A
Group 1 - Verde (Competitor-control) vs. Green (CVI-test)

contact lens

Also known as: methafilcon A
Group 1 - Verde (Competitor-control) vs. Green (CVI-test)

contact lens

Also known as: methafilcon A
Group 2 - Cinza (Competitor-control) vs. Grey (CVI-test)

contact lens

Also known as: methafilcon A
Group 2 - Cinza (Competitor-control) vs. Grey (CVI-test)

contact lens

Also known as: methafilcon A
Group 3 - Esmeralda (Competitor-control) vs. Jade (CVI-test)

contact lens

Also known as: methafilcon A
Group 3 - Esmeralda (Competitor-control) vs. Jade (CVI-test)

contact lens

Also known as: methafilcon A
Group 4 - Azul (Competitor-control) vs. Blue (CVI-test)

contact lens

Also known as: methafilcon A
Group 4 - Azul (Competitor-control) vs. Blue (CVI-test)

Eligibility Criteria

Age18 Years - 40 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Is between 18 and 40 years of age (inclusive).
  • Has had a self-reported visual exam in the last two years.
  • Is an adapted wearer of spherical soft contact lenses.
  • Has a contact lens spherical prescription between - 1.00 and - 10.00 (inclusive).
  • Has a spectacle cylinder up to 0.75 diopter (D) in each eye
  • Can achieve best corrected spectacle distance visual acuity of 20/30 (0.18 logMAR) or better in each eye.
  • Has clear corneas and no active ocular disease.
  • Has read, understood and signed the information consent letter.
  • Is willing to wear his/hers spectacles over the study contact lenses.
  • Is willing to comply with the wear schedule.
  • Is willing to comply with the visit schedule.

You may not qualify if:

  • Has never worn contact lenses before.
  • Currently wears rigid gas permeable contact lenses.
  • Has a history of not achieving comfortable contact lens wear (5 days per week; \> 8 hours/day)
  • Has a contact lens prescription outside the range of - 1.00 to -10.00D.
  • Has a spectacle cylinder ≥1.00D of cylinder in either eye.
  • Does not have a pair of corrective spectacles at the time of the visit.
  • Cannot achieve best corrected spectacle distance visual acuity of 20/30 (0.18 logMAR) or better in each eye.
  • Presence of clinically significant (grade \> 2.0, scale 0-4) anterior segment abnormalities.
  • Presence of ocular or systemic disease or need of medications which might interfere with contact lens wear.
  • Slit lamp findings that would contraindicate contact lens wear such as:
  • Pathological dry eye or associated findings
  • Pterygium, pinguecula, or corneal scars within the visual axis
  • Neovascularization \> 0.75 mm in from of the limbus
  • Giant papillary conjunctivitis (GCP) worse than grade 1
  • Anterior uveitis or iritis (past or present)
  • +8 more criteria

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Optometry Clinic, National Autonomous University

Mexico City, Mexico

Location

MeSH Terms

Conditions

Myopia

Condition Hierarchy (Ancestors)

Refractive ErrorsEye Diseases

Results Point of Contact

Title
Sr. Manager Global Medical Scientific Affairs
Organization
CooperVision

Study Officials

  • Ruben Velazquez Guerrero, MSc FIACLE

    School of Optometry, National Autonomous University (UNAM), Mexico

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
No
Restriction Type
OTHER
Restrictive Agreement
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, INVESTIGATOR
Purpose
OTHER
Intervention Model
PARALLEL
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

November 20, 2014

First Posted

November 24, 2014

Study Start

October 1, 2014

Primary Completion

October 1, 2014

Study Completion

November 1, 2014

Last Updated

March 10, 2017

Results First Posted

August 24, 2016

Record last verified: 2017-01

Locations