NCT02265094

Brief Summary

The aim of this study is to investigate the neural substrates of associative memory in Autism Spectrum Disorder using both behavioural and EEG assessments.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
80

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Dec 2015

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

October 9, 2014

Completed
6 days until next milestone

First Posted

Study publicly available on registry

October 15, 2014

Completed
1.2 years until next milestone

Study Start

First participant enrolled

December 22, 2015

Completed
5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 8, 2020

Completed
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

December 8, 2021

Completed
Last Updated

March 5, 2026

Status Verified

February 1, 2018

Enrollment Period

5 years

First QC Date

October 9, 2014

Last Update Submit

March 3, 2026

Conditions

Autistic Disorder

Keywords

Autism Spectrum DisorderDevelopmentMemoryERD

Outcome Measures

Primary Outcomes (1)

  • Index of discrimination obtained with the task of associative memory

    4 years

Study Arms (2)

Patients

EXPERIMENTAL

Electroencephalography and neuropsychological tests in children with autism

Other: ElectroencephalographyBehavioral: Neuropsychological assessment

Control

EXPERIMENTAL

Electroencephalography and neuropsychological tests in children without autism

Other: ElectroencephalographyBehavioral: Neuropsychological assessment

Interventions

ElectroencephalographyOTHER

EEG recordings during memory tests

ControlPatients
Neuropsychological assessmentBEHAVIORAL

patterns of eye gaze during cognitive tests

ControlPatients

Eligibility Criteria

Age10 Years - 18 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • Right handed children from 10 to 18 years old
  • Informed consent signed by the legal representative and adolescent himself.

You may not qualify if:

  • People with ASD:
  • Participants with ASD without mental retardation with a diagnosis in reference to the DSM V criteria
  • Controls : Participants without ASD
  • mental retardation,
  • schizophrenia,
  • ADHD,
  • head injury with lost of consciousness

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Caen University Hospital

Caen, France

Location

Related Publications (1)

  • Desaunay P, Clochon P, Doidy F, Hinault T, Lambrechts A, Wantzen P, Wallois F, Mahmoudzadeh M, Guile JM, Guenole F, Baleyte JM, Eustache F, Bowler DM, Guillery-Girard B. Intact memory storage but impaired retrieval in visual memory in autism: New insights from an electrophysiological study. Autism Res. 2023 Jan;16(1):99-105. doi: 10.1002/aur.2838. Epub 2022 Nov 1.

    PMID: 36317823RESULT

MeSH Terms

Conditions

Autistic DisorderAutism Spectrum Disorder

Interventions

Neuropsychological Tests

Condition Hierarchy (Ancestors)

Child Development Disorders, PervasiveNeurodevelopmental DisordersMental Disorders

Intervention Hierarchy (Ancestors)

Psychological TestsBehavioral Disciplines and Activities

Study Officials

  • Jean-Marc BALEYTE, MD

    University Hospital, Caen

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
BASIC SCIENCE
Intervention Model
FACTORIAL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 9, 2014

First Posted

October 15, 2014

Study Start

December 22, 2015

Primary Completion

December 8, 2020

Study Completion

December 8, 2021

Last Updated

March 5, 2026

Record last verified: 2018-02

Locations

FR(1)