NCT02205021

Brief Summary

Accumulation of fat in the neck using tape measures has been linked to increased cardiovascular risk. The investigators' hypothesis is that detailed measures of neck fat using computed tomography will show that specific fat compartments in the neck contribute differently to cardiovascular risk.

Trial Health

80
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
303

participants targeted

Target at P75+ for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2014

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2014

Completed
5 months until next milestone

First Submitted

Initial submission to the registry

July 29, 2014

Completed
2 days until next milestone

First Posted

Study publicly available on registry

July 31, 2014

Completed
Last Updated

July 31, 2014

Status Verified

July 1, 2014

Enrollment Period

2 months

First QC Date

July 29, 2014

Last Update Submit

July 30, 2014

Conditions

Obesity

Outcome Measures

Primary Outcomes (1)

  • Relationship of specific neck compartments to cardiovascular risk

    Cardiovascular risk measures were obtained within one year of CT imaging of the neck.

    1 year between PET/CT and cardiometabolic marker measures

Study Arms (1)

All subjects

Other: No intervention

Interventions

No interventionOTHER
All subjects

Eligibility Criteria

Age18 Years - 91 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Retrospective search of whole-body PET/CT examinations and consecutively selected imaging studies.

You may qualify if:

  • no history of malignancy at the time of image acquisition
  • fasting glucose measured immediately prior to PET/CT

You may not qualify if:

  • history of neck cancer, radiation therapy, and/or surgery

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Massachusetts General Hospital

Boston, Massachusetts, 02114, United States

Location

Related Publications (1)

  • Torriani M, Gill CM, Daley S, Oliveira AL, Azevedo DC, Bredella MA. Compartmental neck fat accumulation and its relation to cardiovascular risk and metabolic syndrome. Am J Clin Nutr. 2014 Nov;100(5):1244-51. doi: 10.3945/ajcn.114.088450. Epub 2014 Sep 3.

    PMID: 25332322DERIVED

MeSH Terms

Conditions

Obesity

Condition Hierarchy (Ancestors)

OverweightOvernutritionNutrition DisordersNutritional and Metabolic DiseasesBody WeightSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Martin Torriani, M.D.

    Massachusetts General Hospital

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Professor of Radiology

Study Record Dates

First Submitted

July 29, 2014

First Posted

July 31, 2014

Study Start

January 1, 2014

Primary Completion

March 1, 2014

Last Updated

July 31, 2014

Record last verified: 2014-07

Locations

US(1)