Prevalence of Vitreomacular Adhesion in Patients 40 Years and Older

NCT02160340 | Completed

• 1 other identifier: 11221319Exp
• Study Type: observational
• Target: 1,584
• Locations: 1 country
• Sites: 18

Brief Summary

The purpose of this study is to evaluate the prevalence of vitreomacular adhesion (VMA) in patients 40 years and older using Spectral Domain Optical Coherence Tomography.

Conditions

Vitreomacular Adhesion

Keywords

Posterior Vitreous Detachment; Vitreomacular Traction; Vitreous

Outcome Measures

Primary Outcomes (1)

• What is the overall prevalence of Vitreomacular adhesion in the population 40 years and older?

  Prevalence will be measured using Spectral Domain Optical Coherence Tomography. Tomography scans will be evaluated for the presence or absence of vitreomacular adhesion.

  Two years

Secondary Outcomes (1)

• Is there is a significant correlation between VMA and various maculopathies including diabetic macular edema, retinal vascular occlusion, and age-related macular degeneration?

  2 years

Other Outcomes (1)

• Is VMA more common in males or females?

  2 years

Study Arms (1)

Vitreomacular adhesion

Male or female subjects aged over 40 years with vitreomacular adhesion

Eligibility Criteria

• Age: 40 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Subjects will be selected from primary eye care clinics within academic settings, tertiary care clinics, and veterans administration medical centers.

You may qualify if:

• Clear media

You may not qualify if:

• Prior history of vitreoretinal surgery or pharmacotherapy with intravitreal injection
• Dense media opacity

Sponsors & Collaborators

• Nova Southeastern University: lead
• ThromboGenics: collaborator
• Carl Zeiss Meditec, Inc.: collaborator
• Optovue: collaborator

Study Sites (18)

Schaeffer Eye Center

Birmingham, Alabama, 35216, United States

Location

Leo Semes

Birmingham, Alabama, 35294, United States

Location

Schwartz Laser Eye Center

Scottsdale, Arizona, 85260, United States

Location

VA Greater Los Angeles Healthcare System

Sepulveda, California, 91343, United States

Location

Front Range Eye Associates

Broomfield, Colorado, 80023, United States

Location

Aran Eye Associates

Coral Gables, Florida, 33134, United States

Location

Nova Southeastern University

Fort Lauderdale, Florida, 33328, United States

Location

Retina Macula Specialists of Miami

Miami, Florida, 33126, United States

Location

Murray Ocular Oncology and Retina

Miami, Florida, 33143, United States

Location

Vitreous and Retina Consultants

Winter Haven, Florida, 33880, United States

Location

Clayton Eye Center

Morrow, Georgia, 30260, United States

Location

Indiana University College of Optometry

Indianapolis, Indiana, 46202, United States

Location

Grin Eyecare

Olathe, Kansas, 66061, United States

Location

Jones Eyecare

Albuquerque, New Mexico, 87111, United States

Location

Pacific University College of Optometry

Portland, Oregon, 97205, United States

Location

Larry Alexander

McKinney, Texas, 75070, United States

Location

Retina and Macula Specialists

Tacoma, Washington, 98409, United States

Location

Suburban Opticians

University Place, Washington, 98466, United States

Location

MeSH Terms

Conditions

Vitreous Detachment

Condition Hierarchy (Ancestors)

Eye Diseases

Study Officials

• Julie A Rodman, OD, MS, FAAO

  Nova Southeastern University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 2, 2014
• First Posted: June 10, 2014
• Study Start: May 1, 2014
• Primary Completion: January 1, 2016
• Study Completion: May 1, 2017
• Last Updated: March 29, 2018

Record last verified: 2018-03

Locations

US (18)