NCT02088346

Brief Summary

The purpose is to evaluate the effectiveness and safety profile of telemedicine consultation system in making decision on IV thrombolysis.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
300

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Aug 2014

Geographic Reach
1 country

4 active sites

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

February 27, 2014

Completed
15 days until next milestone

First Posted

Study publicly available on registry

March 14, 2014

Completed
5 months until next milestone

Study Start

First participant enrolled

August 1, 2014

Completed
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2015

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2015

Completed
Last Updated

June 25, 2015

Status Verified

September 1, 2014

Enrollment Period

1 year

First QC Date

February 27, 2014

Last Update Submit

June 23, 2015

Conditions

Keywords

StrokeThrombolysisTissue plasminogen activatorUrokinaseTelemedicine

Outcome Measures

Primary Outcomes (1)

  • Percentage of patients treated with intravenous thrombolysis

    at 4.5 hours

Secondary Outcomes (6)

  • Favorite outcome at 3 months (modified Rankin score ≤2)

    at 1 month/3 months

  • Stroke complications

    at 24 hours/7days

  • Fatal and nonfatal cardiovascular events

    at 7 days

  • All cause mortality

    at 3 months

  • Time intervals

    at 24 hours

  • +1 more secondary outcomes

Study Arms (2)

Teleconsultation

Intravenous thrombolysis guided by telemedicine consultation system based on portable hardwares

Other: Telemedicine consultation system

Historical control

Usual stroke care without the guidance from hub hospital

Interventions

Telemedicine consultation system based on portable hardwares

Teleconsultation

Eligibility Criteria

Age18 Years - 80 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Ischemic stroke patients arriving in the local hospitals within 4.5 hours of symptom onset

You may qualify if:

  • Patients older than 18 years and less than 80 years
  • Acute ischemic stroke
  • Presenting to Emergency Department of spoke hospitals within 4.5 hours of stroke symptom onset
  • National Institutes of Health Stroke Scale (NIHSS) between 4 and 25
  • Signed consent form by the patient or his relatives

You may not qualify if:

  • Time of symptom onset unclear
  • Unlikely to complete study through 3-month follow-up

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (4)

Xingyuan Hospital

Yulin, Shanxi, 719000, China

RECRUITING

Yulin First People's Hospital

Yulin, Shanxi, 719000, China

NOT YET RECRUITING

Yulin Second People's Hospital

Yulin, Shanxi, 719000, China

RECRUITING

Yuyang District People's Hospital

Yulin, Shanxi, 719000, China

NOT YET RECRUITING

Related Publications (1)

  • Yuan Z, Wang B, Li F, Wang J, Zhi J, Luo E, Liu Z, Zhao G. Intravenous thrombolysis guided by a telemedicine consultation system for acute ischaemic stroke patients in China: the protocol of a multicentre historically controlled study. BMJ Open. 2015 May 15;5(5):e006704. doi: 10.1136/bmjopen-2014-006704.

MeSH Terms

Conditions

Stroke

Condition Hierarchy (Ancestors)

Cerebrovascular DisordersBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesVascular DiseasesCardiovascular Diseases

Study Officials

  • Zhirong Liu, MD

    Xijing Hospital

    PRINCIPAL INVESTIGATOR
  • Gang Zhao, MD

    Xijing Hospital

    STUDY DIRECTOR

Central Study Contacts

Ziwen Yuan, MD

CONTACT

Zhirong Liu, MD

CONTACT

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

February 27, 2014

First Posted

March 14, 2014

Study Start

August 1, 2014

Primary Completion

August 1, 2015

Study Completion

November 1, 2015

Last Updated

June 25, 2015

Record last verified: 2014-09

Locations