A Longitudinal Study of Multimodal Resonance Imaging in Stroke Patients
1 other identifier
observational
800
1 country
1
Brief Summary
Imaging of the ischaemic penumbra with a particular diffusion-weighted imaging (DWI)/ perfusion-weighted imaging (PWI) mismatch is a promising approach to the selection of patients with acute ischaemic stroke for trials of intervention. The investigators want to apply multimodal resonance imaging methods such as functional magnetic resonance imaging ( fMRI), diffusion tensor imaging (DTI), arterial spin labeling (ASL) to guide treatment and predict the prognosis of stroke.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Sep 2013
Typical duration for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
September 1, 2013
CompletedFirst Submitted
Initial submission to the registry
December 25, 2013
CompletedFirst Posted
Study publicly available on registry
December 31, 2013
CompletedPrimary Completion
Last participant's last visit for primary outcome
May 1, 2015
CompletedStudy Completion
Last participant's last visit for all outcomes
December 1, 2015
CompletedDecember 31, 2013
December 1, 2013
1.7 years
December 25, 2013
December 30, 2013
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Functional recovery
Participants will be followed till die or lost to follow-up,an expected average of three year.
Secondary Outcomes (1)
Over survival
Participants will be followed till die or lost to follow-up,an expected average of three year
Study Arms (2)
Experimental group
Hospitalized patients with acute stroke.
Control group
Healthy Volunteers.
Eligibility Criteria
Hospitalized patients with stroke and the some healthy volunteers recruited from community
You may qualify if:
- Time from the onset of stroke till hospital within 24 hours. With clinical characteristics such as hemiplegia, headache. Willing and able to comply with the study procedures and provide written informed consent to participate in the study.
- Patients must understand the nature of the study and give informed consent.
You may not qualify if:
- The onset of stroke out of 24 hours. Pregnant women. Patients with intracranial metallic bodies from prior neurosurgical procedure, implanted pacemaker, medication pump, vagal stimulator, deep brain stimulator, TENS unit or ventriculoperitoneal shunt.
- Past history of seizures within one year or unexplained loss of consciousness. Family history of epilepsy.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Zhongda Hospitallead
Study Sites (1)
Zhongda Hospital,Southeast University
Nanjing, Jiangsu, 210009, China
Biospecimen
Extraction of DNA from the blood of patients.
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Gao-jun Teng, Ph.D,MD
Zhongda Hospital
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- CASE CONTROL
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Professor of Radiology & Chair,Department of Radiology
Study Record Dates
First Submitted
December 25, 2013
First Posted
December 31, 2013
Study Start
September 1, 2013
Primary Completion
May 1, 2015
Study Completion
December 1, 2015
Last Updated
December 31, 2013
Record last verified: 2013-12