Attentional Bias Modification Treatment in OCD

NCT02014194 | Completed

• 1 other identifier: 13674113.2.0000.0068
• Study Type: interventional
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

Obsessive-compulsive disorder is a chronic condition. Even with proper treatment, no significant improvement is reached in about 30% to 40% of patients. Thus, the development of new treatment strategies is necessary. The attentional bias - ability to aversive stimuli in capturing the attention of an individual compared to a neutral stimulus - has been extensively studied. Already training attentional bias modification has been shown effective in reducing anxiety present in other anxiety disorders.This project aims to: 1 - generate knowledge on attentional bias in individuals with OCD through the use of a standardized protocol developed for OCD; 2 - available to the scientific community the first specific paradigm for the study of attentional bias in OCD patients, 3 - test the effectiveness of a training protocol for reversing attentional bias in individuals with OCD.

Conditions

Obsessive-compulsive Disorder

Keywords

Attentional Bias; Attentional Bias modification treatment

Outcome Measures

Primary Outcomes (1)

• Percentage of reduction of attentional bias

  Patients will be followed an expected average of 7 weeks (baseline, 2 sessions per week - totalizing 5 weeks, 10 sessions and a session after end of treatment). Measures of attentional bias will be assessed in baseline, session 5 and after session 10.

Secondary Outcomes (1)

• Reduction of anxiety symptoms

  Baseline, session 5 and end of treatment (after session 10) (expected average of 7 weeks)

Study Arms (2)

attentional bias modification, placebo

PLACEBO COMPARATOR

Measure of attentional bias modification treatment after 10 sessions of attentional bias modification (two arms). There are two arms with 15 OCD patients each one.

Behavioral: attentional bias modification treatment

attentional bias modification, active group

ACTIVE COMPARATOR

Measure of attentional bias modification treatment after 10 sessions of attentional bias modification (two arms).

Behavioral: attentional bias modification treatment

Interventions

attentional bias modification treatment BEHAVIORAL

The attentional bias modification treatment is a behavioral computerized program (software e-prime)

attentional bias modification, active group; attentional bias modification, placebo

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• health controls

Sponsors & Collaborators

• Roseli Shavitt: lead

Study Sites (1)

University of Sao Paulo Medical School

São Paulo, 05403010, Brazil

Location

MeSH Terms

Conditions

Obsessive-Compulsive Disorder

Condition Hierarchy (Ancestors)

Anxiety Disorders; Mental Disorders

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: MD, Phd

Study Record Dates

• First Submitted: November 25, 2013
• First Posted: December 18, 2013
• Study Start: November 1, 2013
• Primary Completion: December 1, 2016
• Study Completion: December 1, 2016
• Last Updated: January 25, 2018

Record last verified: 2018-01

Locations

BR (1)