NCT01993082|Completed
Fitness, Cellular Aging, and Caregiver Stress Study
FAST
The Effects of Exercise and Life Stress on Telomere Maintenance and Cardiovascular Disease Risk
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FAST
The Effects of Exercise and Life Stress on Telomere Maintenance and Cardiovascular Disease Risk
Sponsor study identifier
interventional
68
1 country
1
Study Start
January 2014
Actual (reported)Primary Completion
August 2016
Actual (reported)Study Completion
January 2017
Actual (reported)The purpose of this study is to determine whether an aerobic training intervention will alter markers of immune cell aging, improve exercise capacity and blood pressure and decrease psychological distress over 24 weeks in 32 caregivers compared to 32 age-matched wait list control caregivers.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
January 2017
Actual (reported)Click on a node to explore related trials.
Some registry-reported names shown below are not yet linked in this graph.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
November 5, 2013
Actual (reported)November 25, 2013
Actual (reported)January 2014
Actual (reported)August 2016
Actual (reported)January 2017
Actual (reported)Change in Telomerase in Peripheral Blood Mononuclear Cells
Change from Baseline in Telomerase in Peripheral Blood Mononuclear Cells at 24 weeks. Participants will provide blood samples at their baseline study visit, which occurs before the start of the intervention, and at their visit at the end of the 24th week of the study.
Measured at Week 0 (baseline) and Week 24
Change in Cardiovascular Fitness
Measured at Week 0 (baseline) and Week 24
Change in Diastolic and Systolic Blood Pressure
Measured at Week 0 (baseline) and Week 24
For 24 weeks, subjects randomized into the aerobic training group will be asked to increase their physical activity level to meet the Centers for Disease Control and Prevention recommendations for physical activity of 150 minutes per week of moderate activity. A first visit with a fitness coach support provider, followed by weekly coaching texts and phone calls, will provide the framework for the activities in which participants should engage.
Participants randomized into the waitlist control group receive no aerobic training. Wait-list control participants will receive monthly check-in phone calls to establish that they have not significantly increased activity engagement. Participants in this group will receive a free gym membership at the end of the study, monthly phone calls with a fitness coach support provider for 6 months, and 2 coaching text messages per week.
For 24 weeks, subjects randomized into the aerobic training group will be asked to increase their physical activity level to meet the Centers for Disease Control and Prevention recommendations for physical activity of 150 minutes per week of moderate activity. A first visit with a fitness coach support provider, followed by weekly coaching texts and phone calls, will provide the framework for the activities in which participants should engage.
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
University of California, San Francisco
San Francisco, California, 94118, United States
Elissa Epel, PhD
University of California, San Francisco
Samantha Schilf, BA
University of California, San Francisco
68 participants (actual enrollment reported by the registry).
First Submitted
November 5, 2013
First Posted
November 25, 2013
Study Start
January 2014
Actual (reported)CBCT for Parents of Children With Autism
Change in Psychological Well-being (general and daily)
Measured at Week 0 (baseline) and Week 24
Change in Telomere Length in Leukocyte/ Peripheral Blood Mononuclear Cells
Measured at Week 0 (baseline) and Week 24
Change in Mitochondrial Functioning (Enzyme Activity, DNA Copy Number) in Peripheral Blood Mononuclear Cells
Measured at Week 0 (baseline) and Week 24
Contact the study team to confirm eligibility.
Primary Completion
August 2016
Actual (reported)Study Completion
January 2017
Actual (reported)Last Updated
June 13, 2022
Record last verified: 2022-06
Download the complete ClinicalTrials.gov record imported by Syfrah, including fields not shown in this page. The registry may contain a newer revision.
Source: ClinicalTrials.gov.
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