NCT01919658

Brief Summary

The primary objective of the study is to compare motor strength in knee extension between two groups of patients. One group receiving a proximal thigh block of the femoral nerve, and one receiving a distal thigh block of the saphenous nerve. The secondary objective is to compare the pain relief and functional outcomes in these two groups.

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
12

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Jul 2013

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
terminated

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 1, 2013

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

August 6, 2013

Completed
3 days until next milestone

First Posted

Study publicly available on registry

August 9, 2013

Completed
5.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 10, 2019

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 10, 2019

Completed
Last Updated

June 21, 2019

Status Verified

June 1, 2019

Enrollment Period

5.9 years

First QC Date

August 6, 2013

Last Update Submit

June 19, 2019

Conditions

Keywords

nerve blocks in Anterior cruciate ligament surgery

Outcome Measures

Primary Outcomes (1)

  • strength of knee extensors

    Extensor testing will be conducted in both legs using a hand held dynamometer.

    change from baseline preoperatively at 12 months

Secondary Outcomes (1)

  • pain level and functional outcomes

    change from in hospital post-operative period at 12 months

Study Arms (2)

proximal nerve block

ACTIVE COMPARATOR

The anesthesiologist will administer a proximal nerve block if specified in the randomization envelope.

Procedure: nerve block

distal nerve block

ACTIVE COMPARATOR

The anesthesiologist will administer a distal nerve block if specified in the randomization envelope.

Procedure: nerve block

Interventions

nerve blockPROCEDURE

A nerve block performed as per standard of care: femoral nerve blocks, and saphenous nerve blocks performed more distally (within 10cm superior to the adductor tubercle).

distal nerve blockproximal nerve block

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Age 18-65
  • Upcoming ACL reconstruction using patellar tendon autograft scheduled at Hershey Medical Center or the Hershey Outpatient Surgical Center (HOSC)

You may not qualify if:

  • Documented neuropathy
  • Skeletally immature
  • Previous knee surgery
  • Inability to provide informed consent
  • ACL reconstruction with other tendon repairs

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Penn State Hershey Medical Center

Hershey, Pennsylvania, 17033, United States

Location

MeSH Terms

Interventions

Nerve Block

Intervention Hierarchy (Ancestors)

Anesthesia, ConductionAnesthesiaAnesthesia and AnalgesiaDenervationNeurosurgical ProceduresSurgical Procedures, Operative

Study Officials

  • Robert Gallo, MD

    Milton S. Hershey Medical Center

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Assistant Professor of Orthopaedic Surgery Sports Medicine

Study Record Dates

First Submitted

August 6, 2013

First Posted

August 9, 2013

Study Start

July 1, 2013

Primary Completion

June 10, 2019

Study Completion

June 10, 2019

Last Updated

June 21, 2019

Record last verified: 2019-06

Locations