NCT01891253

Unknown

Inert Gas Rebreathing in Ventilated Patients

Universitätsmedizin Mannheim Source

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Other study identifiers

Sponsor study identifier

VIGR_MA

Study Type

observational

Estimated enrollment

50

Locations

1 country

Sites

1

Timeline

Study Start

March 2013

Actual (reported)

Primary Completion

December 2020

Estimated (date passed)

This estimate has passed. The registry has not confirmed an actual date for this milestone.

Study Completion

December 2020

Estimated (date passed)

This estimate has passed. The registry has not confirmed an actual date for this milestone.

Brief Summary

Measuring hemodynamic parameters in ventilated patients is important yet still complicated to perform. Inert gas rebreathing (IGR) showed promising results when being compared to other invasive as well as non-invasive techniques for the measurement of cardiac output. The aim of our study is to evaluate the feasibility of IGR in ventilated patients.

Registry Overview

Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.

Recruitment status: unknown
Estimated enrollment: 50 participants
Study completion date: December 2020
Estimated (date passed)
This estimate has passed. The registry has not confirmed an actual date for this milestone.
Listed locations: 1 countries · 1 sites

Trial Relationships

Click on a node to explore related trials.

Some registry-reported names shown below are not yet linked in this graph.

Study Timeline

Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.

Study Start
March 2013
Actual (reported)
First Submitted
June 20, 2013
Actual (reported)
First Posted
July 3, 2013
Actual (reported)
Primary Completion
December 2020
Estimated (date passed)
This estimate has passed. The registry has not confirmed an actual date for this milestone.
Study Completion
December 2020
Estimated (date passed)
This estimate has passed. The registry has not confirmed an actual date for this milestone.

Last Updated: September 25, 2019
Status Verified: September 2019
Last Update Submitted: September 24, 2019

Conditions

Heart Failure Renal Failure Respiratory Failure Sepsis

Keywords

cardiac outputmechanical ventilationinert gas rebreathingpulse contour analysis

Outcome Measures

Primary Outcomes (1)

cardiac output
Determination of cardiac output using invasive pulse contour analysis (PiCCO) and non-invasive inert gas rebreathing (Innocor)
1 day

Study Arms (1)

ventilated patients

ventilated patients in an internal medicine ICU with existing PiCCO invasive hemodynamic monitoring

Device: non-invasive determination of cardiac output

Interventions

non-invasive determination of cardiac outputDevice

ventilated patients

Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.

Eligibility Criteria

Age18 Years - 80 Years

Sexall

Healthy VolunteersNo

Age GroupsAdult (18-64), Older Adult (65+)

Sampling MethodNon-Probability Sample

Study Population

ventilated ICU patients

You may qualify if:

age 18 - 80 years

Sponsors & Collaborators

Universitätsmedizin Mannheim
Otherlead

Study Sites (1)

Universitätsmedizin Mannheim

Manheim, Baden-Wurttemberg, 68167, Germany

MeSH Terms

Conditions

SepsisRespiratory InsufficiencyHeart FailureRenal Insufficiency

Condition Hierarchy (Ancestors)

InfectionsSystemic Inflammatory Response SyndromeInflammationPathologic ProcessesPathological Conditions, Signs and SymptomsRespiration DisordersRespiratory Tract DiseasesHeart DiseasesCardiovascular DiseasesKidney DiseasesUrologic Diseases

Study Officials

Joachim Saur, MD
Universitätsmedizin Mannheim
PRINCIPAL INVESTIGATOR

Study Design

Study Type: observational
Observational Model: COHORT
Time Perspective: PROSPECTIVE
Sponsor Type: OTHER
Responsible Party: PRINCIPAL INVESTIGATOR
PI Title: Priv.-Doz. Dr. med.

Study Record Dates

First Submitted

June 20, 2013

First Posted

July 3, 2013

Study Start

March 2013

Actual (reported)

Primary Completion

December 2020

Estimated (date passed)

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Unknown

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Phase 3Completed

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Completed

NCT03074253

Cardiovascular Imaging and Biomarker Analyses (CIBER)

Unknown

mechanically ventilated patient

existing PiCCO arterial line

You may not qualify if:

FiO2 \> 60% (fraction of inspired oxygen)
PEEP \> 10 mmHg (positive end-expiratory pressure)
SO2 \< 90% (oxygen saturation )
Systolic blood pressure \< 90 mmHg
Heart rate \> 150 bpm
APRV (airway pressure release ventilation)
ICD (implantable cardioverter defibrillator) / pace maker
\[ Anaesthetic Conserving Device (Anaconda) \]

Contact the study team to confirm eligibility.

Female Urogenital Diseases

Female Urogenital Diseases and Pregnancy Complications

Urogenital Diseases

Male Urogenital Diseases

This estimate has passed. The registry has not confirmed an actual date for this milestone.

Study Completion

December 2020

Estimated (date passed)

This estimate has passed. The registry has not confirmed an actual date for this milestone.

Last Updated

September 25, 2019

Record last verified: 2019-09

Source record

Download the complete ClinicalTrials.gov record imported by Syfrah, including fields not shown in this page. The registry may contain a newer revision.

Source: ClinicalTrials.gov.

JSON downloads include source attribution and retrieval details alongside the unchanged original record or the separately normalized values.

Registry identifier: NCT01891253
Data provider: ClinicalTrials.gov
Source updated: 2019-09-25
Normalization version: ctgov-legacy-1

Open registry record

Source retrieved: 2026-10-25 22:31:25 UTC

Locations

DE(1)

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

Study Start

First Submitted

First Posted

Primary Completion

Study Completion

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Study Arms (1)

ventilated patients

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Study Officials

Study Design

Study Record Dates

You may not qualify if:

Source record

Locations