Cognitive Behavior Therapy for Depression

NCT01868711 | Completed

• 2 other identifiers: 6806RR21MH121915-01A1
• Study Type: interventional
• Target: 150
• Locations: 1 country
• Sites: 1

Brief Summary

Psychological mindedness(PM) is a metacognitive process in which the person uses his cognitive and affective abilities to understand his thoughts, feelings, and his behaviors as they interact with his internal experiences and his external experiences in the world. It dynamically modifies his behavior to move towards self-actualization in a manner positive to himself and the world. We investigate whether the assessment of PM can distinguish depressed patients who benefit from CBT.

Conditions

Depression

Keywords

Cognitive Behavior Therapy; Self-awarness; Supportive Therapy; Virtual psychotherapy

Outcome Measures

Primary Outcomes (1)

• Level of depression as measured by the Hamilton Depression Rating Scale

  Outcome measure of depression will be assessed as the change in depression between baseline (pre-treatment) and post treatment (up to 12 weeks).

  Up to 12 weeks.

Study Arms (2)

*Cognitive behavior therapy

ACTIVE COMPARATOR

Depressed patients will receive 12 virtual sessions of cognitive behavior therapy (CBT) for depression. CBT Includes behavior activation, correcting distorted thoughts, and other tools to reduce symptoms.

Behavioral: Cognitive Behavior Therapy

Supportive psychotherapy

OTHER

Supportive psychotherapy aims to strengthen the patient's ability to cope effectively with various life stressors. Specifically, in our study, supportive psychotherapy will be geared towards reducing or alleviating symptoms of depression. The sessions will be administered virtually.

Behavioral: Cognitive Behavior Therapy

Interventions

Cognitive Behavior Therapy BEHAVIORAL

Also known as: Supportive psychotherapy

*Cognitive behavior therapy; Supportive psychotherapy

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Males or females between the ages of 18 and 65 (inclusive).
• Primary DSM-IV-TR diagnosis of major depression
• A negative urine toxicology, i.e., a urine specimen that does not test positive for the use of drugs of abuse or use of benzodiazepines.
• Ability to give informed consent.
• Fluent in English

You may not qualify if:

• Patients who have a "lifetime" history of Schizophrenia or other current psychotic disorder, Major Depressive Disorder with Psychotic or Catatonic features, Bipolar I Affective Disorder, or Organic Mental Disease.
• DSM-V substance abuse or dependence within the past 6 months (except nicotine or caffeine).
• Active suicidal or homicidal ideation, or judged to be at serious suicide risk.
• Any unstable medical or neurological condition.
• Presently receiving psychotherapy or psychotropic medications.
• Prior History of CBT for Depression treatment failure.
• Left-handedness

Sponsors & Collaborators

• New York State Psychiatric Institute: lead
• National Institute of Mental Health (NIMH): collaborator

Study Sites (1)

New York State Psychiatric Institute

New York, New York, 10032, United States

Location

Related Links

• Click here for more information about the study

MeSH Terms

Conditions

Depression

Interventions

Cognitive Behavioral Therapy

Condition Hierarchy (Ancestors)

Behavioral Symptoms; Behavior

Intervention Hierarchy (Ancestors)

Behavior Therapy; Psychotherapy; Behavioral Disciplines and Activities

Study Officials

• Ronit Kishon, Ph.D.

  New York State Psychiatric Institute, Columbia University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor of Psychology

Model Details: Depressed patients will be randomized between cognitive behavor therapy and supportive therapy.

Study Record Dates

• First Submitted: May 20, 2013
• First Posted: June 4, 2013
• Study Start: July 1, 2013
• Primary Completion: June 1, 2023
• Study Completion: June 2, 2023
• Last Updated: May 17, 2024

Record last verified: 2024-05

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)