A 1-Year, Multicenter, Randomized, Open-Label Controlled Study to Evaluate the Efficacy and Safety of Cord Blood Cells Expanded With MPCs for Hematopoetic Recovery in Patients With Hematologic Malignancies After Myeloablative Treatment
Sponsor study identifier
Secondary identifiers
OTHER · UT MDACC
interventional
49
1 country
9
Study Start
August 2013
Actual (reported)Primary Completion
September 23, 2016
Actual (reported)Study Completion
May 5, 2017
Actual (reported)The study investigates the time to engraftment of a mesenchymal expanded cord blood unit in patients with hematologic malignancies undergoing transplantation with myeloablative conditioning.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
May 5, 2017
Actual (reported)Click on a node to explore related trials.
Some registry-reported names shown below are not yet linked in this graph.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
May 13, 2013
Actual (reported)May 15, 2013
Actual (reported)August 2013
Actual (reported)September 23, 2016
Actual (reported)May 5, 2017
Actual (reported)Time to Neutrophil and Platelet Engraftment
100 days
Proportion of subjects with neutrophil recovery at day 26, platelet recovery at day 60 and subjects alive at day 100
100 days
Percentage of patients with primary graft failure
100 days
Infusion of one MPC expanded cord unit and one unexpanded cord unit.
Infusion of two unexpanded cord blood units.
Infusion of one MPC expanded cord unit and one unexpanded cord unit.
Umbilical Cord Blood.
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
University of Miami Health System Sylvester Comprehensive Cancer Center
Miami, Florida, 33136, United States
Moffitt Cancer Center
Tampa, Florida, 33612, United States
Beth Israel Deaconess Medical Center
Boston, Massachusetts, 02215, United States
Memorial Sloan Kettering Cancer Center
New York, New York, 10065, United States
Weill Cornell-New York Presbyterian Hospital
New York, New York, 10065, United States
Westchester Medical Center
Valhalla, New York, 10595, United States
Case Western
Donna Skerrett, MD, MS
Mesoblast, Ltd.
Elizabeth J. Shpall, MD
M.D. Anderson Cancer Center
49 participants (actual enrollment reported by the registry).
First Submitted
May 13, 2013
First Posted
May 15, 2013
Study Start
August 2013
Actual (reported)Primary Completion
Incidence and severity of acute Graft Versus Host Disease
100 days
Contact the study team to confirm eligibility.
Cleveland, Ohio, 44106, United States
MD Anderson Cancer Center
Houston, Texas, 77030, United States
Texas Transplant Center at Methodist Healthcare System
San Antonio, Texas, 78229, United States
September 23, 2016
Actual (reported)Study Completion
May 5, 2017
Actual (reported)Last Updated
June 26, 2020
Record last verified: 2020-06
Download the complete ClinicalTrials.gov record imported by Syfrah, including fields not shown in this page. The registry may contain a newer revision.
Source: ClinicalTrials.gov.
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