Key Insights

Highlights

Success Rate

78% trial completion

Published Results

121 trials with published results (30%)

Research Maturity

248 completed trials (62% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 59/100

Termination Rate

18.0%

72 terminated out of 400 trials

Success Rate

77.5%

-9.0% vs benchmark

Late-Stage Pipeline

10%

40 trials in Phase 3/4

Results Transparency

49%

121 of 248 completed with results

Key Signals

121 with results78% success72 terminated

Data Visualizations

Phase Distribution

362Total
Not Applicable (21)
Early P 1 (5)
P 1 (154)
P 2 (142)
P 3 (29)
P 4 (11)

Trial Status

Completed248
Terminated72
Unknown34
Recruiting23
Active Not Recruiting13
Withdrawn8

Trial Success Rate

77.5%

Benchmark: 86.5%

Based on 248 completed trials

Clinical Trials (400)

Showing 20 of 20 trials
NCT04728893Phase 2Recruiting

Efficacy and Safety of Nemtabrutinib (MK-1026) in Participants With Hematologic Malignancies (MK-1026-003)

NCT03075696Phase 1Active Not RecruitingPrimary

A Dose Escalation Study of Glofitamab (RO7082859) as a Single Agent and in Combination With Obinutuzumab, Administered After a Fixed, Single Pre-treatment Dose of Obinutuzumab in Participants With Relapsed/Refractory B-cell Non-hodgkin's Lymphoma

NCT03226704Enrolling By Invitation

Leukapheresis for CAR or Adoptive Cell Therapy Manufacturing

NCT04002947Phase 2RecruitingPrimary

Acalabrutinib With DA-EPOCH-R or R-CHOP for People With Untreated Diffuse Large B-cell Lymphoma

NCT07620314Phase 1RecruitingPrimary

Safety and Efficacy of KSVCBD Injection in B-cell Non-Hodgkin's Lymphoma Expressing CD19 and/or BCMA

NCT00923442Enrolling By Invitation

Biology Studies of Hematologic Cancers

NCT03533283Phase 1Active Not RecruitingPrimary

An Open-Label Phase lB/II Study of Glofitamab and Atezolizumab or Polatuzumab Vedotin in Adult Patients With Relapsed/Refractory B-Cell Non-Hodgkin's Lymphoma

NCT00710892Phase 1Active Not Recruiting

CASPALLO: Allodepleted T Cells Transduced With Inducible Caspase 9 Suicide Gene

NCT01840566Phase 1Active Not RecruitingPrimary

High Dose Therapy and Autologous Stem Cell Transplantation Followed by Infusion of Chimeric Antigen Receptor (CAR) Modified T-Cells Directed Against CD19+ B-Cells for Relapsed and Refractory Aggressive B Cell Non-Hodgkin Lymphoma

NCT03789097Phase 1CompletedPrimary

Vaccination With Flt3L, Radiation, and Poly-ICLC

NCT03844048Phase 3Active Not Recruiting

An Extension Study of Venetoclax for Subjects Who Have Completed a Prior Venetoclax Clinical Trial

NCT05618028Phase 1Active Not Recruiting

Study to Evaluate Adverse Events and Change in Disease Activity in Adult Participants With B-Cell Malignancies Receiving Oral ABBV-525 Tablets

NCT00131014RecruitingPrimary

Establishing a Tumor Bank in Families With Multiple Lymphoproliferative Malignancies

NCT01890486Recruiting

The Prospective Collection, Storage and Reporting of Data on Patients Undergoing Hematopoietic Stem Cell Transplantation Utilizing a Standard Preparative Regimen

NCT03789240Phase 2Active Not Recruiting

Response-Adapted Therapy With Copanlisib and Rituximab in Untreated Follicular Lymphoma

NCT01555892Phase 1Recruiting

Cytotoxic T-Lymphocytes for EBV-positive Lymphoma, GRALE

NCT03198026Phase 2Active Not RecruitingPrimary

Obinutuzumab and Ibrutinib as Front Line Therapy in Treating Patients With Indolent Non-Hodgkin's Lymphomas

NCT01192464Phase 1Active Not Recruiting

EBV CTLs Expressing CD30 Chimeric Receptors For CD 30+ Lymphoma

NCT03123029Unknown

Expanded Access to Venetoclax

NCT06667687Phase 1RecruitingPrimary

Study to Evaluate Adverse Events, Change in Disease Activity, and How Intravenously Infused ABBV-291 Moves Through the Body in Adult Participants With Non-Hodgkin's Lymphoma

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